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Invitrogen
Arginase 2 Monoclonal Antibody (GT11111)
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Product Details
MA5-27815
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
GT11111
Immunogen
Recombinant protein encompassing a sequence within the center region of human ARG2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2735112
Product Specific Information
Positive Control: mouse kidney
Predicted Reactivity: Human (100%), Dog (85%), Rabbit (90%), Chicken (81%), Rhesus Monkey (99%), Bovine (93%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AII type II arginase; Arginase II; arginase type II; arginase, type II; Arginase-2, mitochondrial; kidney arginase; Kidney-type arginase; L-arginine amidinohydrolase; L-arginine ureahydrolase; Non-hepatic arginase; nonhepatic arginase; Type II arginase
Gene Aliases: AII; ARG2; AU022422
UniProt ID: (Human) P78540, (Rat) O08701, (Mouse) O08691
Entrez Gene ID: (Human) 384, (Rat) 29215, (Mouse) 11847
urea cycle
ureteric bud development
response to hypoxia
arginine metabolic process
apoptotic process
striated muscle contraction
midgut development
response to nutrient
response to herbicide
response to hormone
response to glucose
response to selenium ion
regulation of L-arginine import
response to amine
arginine catabolic process to ornithine
lung development
response to vitamin E
response to drug
response to amino acid
regulation of nitric oxide biosynthetic process
negative regulation of striated muscle contraction
response to cadmium ion
response to mercury ion
response to axon injury
negative regulation of nitric-oxide synthase activity
maternal process involved in female pregnancy
cellular response to lipopolysaccharide
cellular response to interferon-gamma
cellular response to interleukin-4
cellular response to dexamethasone stimulus
nitric oxide biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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