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Invitrogen
Arp2 Polyclonal Antibody
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FIGURE: 1 / 2
Arp2 Antibody (PA5-17311) in ICC/IF
Immunofluorescence analysis of Arp2 was performed using MCF7 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with Arp2 Polyclonal Antibody (Product # PA5-17311) at 1:100 dilution in 0.1% BSA and incubated overnight at 4 degree and then labeled with Goat anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32731) at a dilution of 1:2000 for 45 mi... View More
Product Details
PA5-17311
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Fruit fly,
Hamster,
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to the sequence of human ARP2
Conjugate
Form
Liquid
Concentration
24 µg/mL
Purification
Affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10980021
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
ARP2 (actin-related protein 2) is an ATP-binding component of the ARP2/3 complex - a multiprotein complex that mediates actin polymerization upon stimulation by the nucleation-promoting factor (NPF). The ARP2/3 complex mediates the formation of branched actin networks in the cytoplasm and provides the force for cell motility. The ARP2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Actin-like protein 14D; Actin-like protein 2; Actin-related protein 14 Da; Actin-related protein 14D; Actin-related protein 2; Arp14D; ARP2 actin-related protein 2 homolog; ARP2 actin-related protein 2 homolog (yeast); Arp2-PA; Arp2-PB; Arp2-PC; CG9901-PA; CG9901-PB; CG9901-PC
Gene Aliases: 4921510D23Rik; AA409782; Actr14D; ACTR2; ARP14D; ARP2; CG9901; D6Ertd746e; Dmel\CG9901; Dmel_CG9901; I79_003843
UniProt ID: (Human) P61160, (Rat) Q5M7U6, (Mouse) P61161, (Fruit fly) P45888
Entrez Gene ID: (Human) 10097, (Rat) 289820, (Mouse) 66713, (Chinese hamster) 100752591, (Fruit fly) 32623
movement of cell or subcellular component
establishment or maintenance of cell polarity
asymmetric cell division
meiotic chromosome movement towards spindle pole
cytosolic transport
meiotic cytokinesis
Arp2/3 complex-mediated actin nucleation
Fc-gamma receptor signaling pathway involved in phagocytosis
cilium assembly
ephrin receptor signaling pathway
spindle localization
cell morphogenesis
cytoskeleton organization
actin filament organization
regulation of actin polymerization or depolymerization
sensory perception of pain
positive regulation of synaptic growth at neuromuscular junction
regulation of filopodium assembly
terminal button organization
actin cytoskeleton organization
meiotic cell cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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