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Invitrogen
Arp2 Polyclonal Antibody
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FIGURE: 1 / 5
Arp2 Antibody (PA5-27879) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of Arp2 was performed in HeLa cells fixed in 4% paraformaldehyde at RT for 15 min. Green: Arp2 Polyclonal Antibody (Product # PA5-27879) diluted at 1:100. Red: phalloidin, a cytoskeleton marker. Blue: Hoechst 33342 staining.
Product Details
PA5-27879
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Arp2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2545355
Product Specific Information
Recommended positive controls: H1299, HeLa, HepG2, Molt-4, Raji, NIH-3T3.
Predicted reactivity: Mouse (100%), Rat (99%), Xenopus laevis (98%), Pig (100%), Chicken (99%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
ARP2 (actin-related protein 2) is an ATP-binding component of the ARP2/3 complex - a multiprotein complex that mediates actin polymerization upon stimulation by the nucleation-promoting factor (NPF). The ARP2/3 complex mediates the formation of branched actin networks in the cytoplasm and provides the force for cell motility. The ARP2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Actin-like protein 2; Actin-related protein 2; ARP2 actin-related protein 2 homolog
Gene Aliases: 4921510D23Rik; AA409782; ACTR2; ARP2; D6Ertd746e
UniProt ID: (Human) P61160, (Rat) Q5M7U6, (Mouse) P61161
Entrez Gene ID: (Human) 10097, (Rat) 289820, (Mouse) 66713
movement of cell or subcellular component
establishment or maintenance of cell polarity
asymmetric cell division
meiotic chromosome movement towards spindle pole
cytosolic transport
meiotic cytokinesis
Arp2/3 complex-mediated actin nucleation
Fc-gamma receptor signaling pathway involved in phagocytosis
cilium assembly
ephrin receptor signaling pathway
spindle localization
actin cytoskeleton organization
meiotic cell cycle
actin filament organization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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