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Product Details
OSA00247W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from aa region 2-50 of human Atlastin-1 conjugated to an immunogenic carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide shares 94% identity with mouse and rat sequences.
Specificity of this antibody: Atlastin-1.
Target Information
The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ATL1 alpha; ATL1 beta; ATL1 gamma; ATL1-delta; Atlastin-1; BCL-11B; Bcl11B; BCL11B/TRDC fusion; Brain-specific GTP-binding protein; Ctip 2; CTIP-2; CTIP2; GBP-3; GTP-binding protein 3; Guanine nucleotide-binding protein 3; guanylate-binding protein 3; hGBP3; hRit1; hRIT1 alpha; Rit 1; Rit1; Spastic paraplegia 3 protein A; ZNF856B
Gene Aliases: AD-FSP; ATL1; atlastin1; FSP1; GBP3; HSN1D; SPG3; SPG3A
UniProt ID: (Human) Q8WXF7
Entrez Gene ID: (Human) 51062
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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