Proteintech

B3GALT2 Polyclonal Antibody

View all (5) B3GALT2 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Product Details

14177-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

B3GALT2 Fusion Protein Ag5384 (47-422 aa encoded by BC022507)
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: DWLPGRAGF KENPVTYTFR GFRSTKSETN HSSLRNIWKE TVPQTLRPQT ATNSNNTDLS PQGVTGLENT LSANGSIYNE KGTGHPNSYH FKYIINEPEK CQEKSPFLIL LIAAEPGQIE ARRAIRQTWG NESLAPGIQI TRIFLLGLSI KLNGYLQRAI LEESRQYHDI IQQEYLDTYY NLTIKTLMGM NWVATYCPHI PYVMKTDSDM FVNTEYLINK LLKPDLPPRH NYFTGYLMRG YAPNRNKDSK WYMPPDLYPS ERYPVFCSGT GYVFSGDLAE KIFKVSLGIR RLHLEDVYVG ICLAKLRIDP VPPPNEFVFN HWRVSYSSCK YSHLITSHQF QPSELIKYWN HLQQNKHNAC ANAAKEKAGR YRHRKLH (47-422 aa encoded by BC022507)

Target Information

This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene encodes a protein that functions in N-linked glycoprotein glycosylation and shows strict donor substrate specificity for UDP-galactose.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Beta-1,3-galactosyltransferase 2; Beta-1,3-GalTase 2; beta-3-galt2; beta3Gal-T2; beta3GalT2; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase 2; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase-II; UDP-galactose:2-acetamido-2-deoxy-D-glucose 3beta-galactosyltransferase 2

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Gene Aliases: B3GALT2; beta3Gal-T2; BETA3GALT2; GLCT2

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UniProt ID: (Human) O43825, (Mouse) O54905

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Entrez Gene ID: (Human) 8707, (Mouse) 26878, (Rat) 686081

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Function(s)
UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity alpha-1,6-mannosyltransferase activity alpha-1,2-mannosyltransferase activity mannosyltransferase activity alpha-1,3-mannosyltransferase activity alpha-1,3-galactosyltransferase activity UDP-glucose:glycoprotein glucosyltransferase activity glycolipid mannosyltransferase activity oligosaccharyl transferase activity dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity acetylglucosaminyltransferase activity acetylgalactosaminyltransferase activity galactosyltransferase activity fucosyltransferase activity O antigen polymerase activity lipopolysaccharide-1,6-galactosyltransferase activity transferase activity transferase activity, transferring glycosyl groups cellulose synthase activity 9-phenanthrol UDP-glucuronosyltransferase activity 1-phenanthrol glycosyltransferase activity 9-phenanthrol glycosyltransferase activity 1,2-dihydroxy-phenanthrene glycosyltransferase activity phenanthrol glycosyltransferase activity beta-1,4-mannosyltransferase activity alpha-1,2-galactosyltransferase activity dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity lipopolysaccharide-1,5-galactosyltransferase activity dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity inositol phosphoceramide synthase activity glucosyltransferase activity alpha-(1->3)-fucosyltransferase activity alpha-(1->6)-fucosyltransferase activity indole-3-butyrate beta-glucosyltransferase activity salicylic acid glucosyltransferase (ester-forming) activity salicylic acid glucosyltransferase (glucoside-forming) activity benzoic acid glucosyltransferase activity chondroitin hydrolase activity dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity cytokinin 9-beta-glucosyltransferase activity
Process(es)
protein glycosylation oligosaccharide biosynthetic process
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