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Immunogen sequence: STRDAPGLRL PLAPWAPPQS PRRPELPDLA PEPRYAHIPV RIKEQVVGLL AWNNCSCESS GGGLPLPFQK QVRAIDLTKA FDPAELRAAS ATREQEFQAF LSRSQSPADQ LLIAPANSPL QYPLQGVEVQ PLRSILVPGL SLQAASGQEV YQVNLTASLG TWDVAGEVTG VTLTGEGQAD LTLVSPGLDQ LNRQLQLVTY SSRSYQTNTA DTGAR
GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: (N-acetylneuraminyl)-galactosylglucosylceramide; Beta-1,4 N-acetylgalactosaminyltransferase 1; beta-1,4-N-acetyl-galactosaminyl transferase 1; beta1,4GalNAc-T; GalNAc-T; GD2 synthase, GM2 synthase; GM2/GD2 synthase; UDP-Gal:betaGlcNAc beta-1,4-N-acetylgalactosaminyltransferase transferase 1; UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase (GalNAc-T)
Gene Aliases: B4GALNT1; GALGT; GalNAc-T; GALNACT; SIAT2; SPG26
UniProt ID: (Human) Q00973
Entrez Gene ID: (Human) 2583
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