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Abnova
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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MPSTQLLAAA AAAATAPGPT PPPLAPGSLR SPVPCPVPRL PRCHPVLTRH LVLRVHRENP GVLMGGRYTP PDCTPAQTVA VIIPFRHREH HLRYWLHYLH PILRRQRLRY GVYVINQHGE DTFNRAKLLN VGFLEALKED AAYDCFIFSD VDLVPMDDRN LYRCGDQPRH FAIAMDKFGF RLPYAGYFGG VSGLSKAQFL RINGFPNEYW GWGGEDDDIF NRISLTGMKV SRPDIRIGRY RMIKHDRDKH NEPNPQRFTK IQNTKLTMKR DGIGSVRYQV LEVSRQPLFT NITVDIGRPP SWPPRG
B4GALT2 is one of type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 4-Gal; Beta-1,4-galactosyltransferase 2; Beta-1,4-GalTase 2; beta-4-GalT2; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 2; Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; Lactose synthase A protein; N-acetyllactosamine synthase; Nal synthase; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 2; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2; UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 2; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2
Gene Aliases: B4Gal-T2; B4Gal-T3; B4GALT2; beta4Gal-T2
UniProt ID: (Human) O60909
Entrez Gene ID: (Human) 8704
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