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Invitrogen
BAG1 Polyclonal Antibody
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Product Details
PA1-30414
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide mapping to the carboxy terminus of mouse Bag-1.
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 0.2% gelatin
Contains
0.1% sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Wet ice
RRID
AB_2290178
Product Specific Information
Recommended positive controls: HL-60.
Target Information
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least three protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site, and alternative, downstream, AUG translation initiation sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BAG family molecular chaperone regulator 1; BAG-1; Bcl-2 associating athanogene-1 protein; Bcl-2-associated athanogene 1; Bcl-2-binding protein; BCL2-associated athanogene; glucocortoid receptor-associated protein RAP46; receptor-associated protein, 46-KD; RP11-326F20.2
Gene Aliases: BAG-1; BAG1; HAP; RAP46
UniProt ID: (Human) Q99933, (Mouse) Q60739, (Rat) B0K019
Entrez Gene ID: (Human) 573, (Mouse) 12017, (Rat) 297994
negative regulation of protein phosphorylation
apoptotic process
neuron differentiation
negative regulation of apoptotic process
positive regulation of neuron apoptotic process
positive regulation of transcription from RNA polymerase II promoter
chaperone cofactor-dependent protein refolding
protein localization to mitochondrion
negative regulation of motor neuron apoptotic process
response to lithium ion
response to organic cyclic compound
response to nicotine
response to drug
cell surface receptor signaling pathway
regulation of catalytic activity
regulation of cellular response to heat
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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