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Immunogen sequence: RHGHKELKKI FEDFSIQEID INNEQENDYE EDIASFSTYI PSTQNPAFHH ESRKTYGQSA DGAEANEMEG EGKQNGSGME TKHSPL
Highest antigen sequence identity to the following orthologs: Mouse - 50%, Rat - 55%.
The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B-cell scaffold protein with ankyrin repeats
Gene Aliases: BANK; BANK1
UniProt ID: (Human) Q8NDB2
Entrez Gene ID: (Human) 55024
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