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Product Details
16099-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BBOX1 Fusion Protein Ag8964 (1-387 aa encoded by BC011034)
Conjugate
Form
Liquid
Concentration
0.36 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MACTIQKAE ALDGAHLMQI LWYDEEESLY PAVWLRDNCP CSDCYLDSAK ARKLLVEALD VNIGIKGLIF DRKKVYITWP DEHYSEFQAD WLKKRCFSKQ ARAKLQRELF FPECQYWGSE LQLPTLDFED VLRYDEHAYK WLSTLKKVGI VRLTGASDKP GEVSKLGKRM GFLYLTFYGH TWQVQDKIDA NNVAYTTGKL SFHTDYPALH HPPGVQLLHC IKQTVTGGDS EIVDGFNVCQ KLKKNNPQAF QILSSTFVDF TDIGVDYCDF SVQSKHKIIE LDDKGQVVRI NFNNATRDTI FDVPVERVQP FYAALKEFVD LMNSKESKFT FKMNPGDVIT FDNWRLLHGR RSYEAGTEIS RHLEGAYADW DVVMSRLRIL RQRVENGN (1-387 aa encoded by BC011034)
Target Information
BBOX1 encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1; butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase); Gamma-BBH; Gamma-butyrobetaine dioxygenase; Gamma-butyrobetaine hydroxylase; Gamma-butyrobetaine,2-oxoglutarate dioxygenase; gamma-butyrobetaine,2-oxoglutarate dioxygenase 1
Gene Aliases: AI874739; BBH; BBOX; BBOX1; G-BBH; gamma-BBH
UniProt ID: (Human) O75936, (Rat) Q9QZU7, (Mouse) Q924Y0
Entrez Gene ID: (Human) 8424, (Rat) 64564, (Mouse) 170442
iron ion binding
protein binding
zinc ion binding
gamma-butyrobetaine dioxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
oxidoreductase activity
metal ion binding
dioxygenase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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