Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Osenses
BBS2 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 5
BBS2 Antibody (OSB00030W-100UL) in IHC (P)
IHC-P on paraffin sections of human testis. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using HRP polymer. Primary antibody: dilution 1:1000, incubated 30 min at RT using Autostainer. Sections were counterstained with Harris Hematoxylin.
Product Details
OSB00030W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from the n-terminal region of human BBS2 conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in rat and mouse.
Specificity of this antibody: BBS2.
Target Information
This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene forms a multiprotein BBSome complex with six other BBS proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Bardet-Biedl syndrome 2 homolog; Bardet-Biedl syndrome 2 protein; Bardet-Biedl syndrome 2 protein homolog; BBSome complex member BBS2; MGC20703
Gene Aliases: 2410125H22Rik; AI447581; BBS; BBS2; RP74
UniProt ID: (Human) Q9BXC9, (Rat) Q99MH9, (Mouse) Q9CWF6
Entrez Gene ID: (Human) 583, (Rat) 113948, (Mouse) 67378
sperm axoneme assembly
visual perception
protein localization
negative regulation of gene expression
artery smooth muscle contraction
striatum development
hippocampus development
cerebral cortex development
adult behavior
melanosome transport
protein localization to organelle
nonmotile primary cilium assembly
negative regulation of appetite by leptin-mediated signaling pathway
negative regulation of multicellular organism growth
positive regulation of multicellular organism growth
vasodilation
cilium assembly
Golgi to plasma membrane protein transport
fat cell differentiation
photoreceptor cell maintenance
brain morphogenesis
cartilage development
cilium morphogenesis
regulation of cilium beat frequency involved in ciliary motility
protein localization to ciliary membrane
biological_process
leptin-mediated signaling pathway
response to leptin
transport
protein transport
cell projection organization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support