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          • Primary Antibodies ›
          • BBS5 Antibodies

          Proteintech

          BBS5 Polyclonal Antibody

          33 References
          View all (8) BBS5 antibodies

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          Datasheet
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          Cite BBS5 Polyclonal Antibody

          • Antibody Testing Data (17)
          BBS5 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          BBS5 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 17

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          BBS5 Antibody (14569-1-AP) in ICC/IF

          IF result from Dr. Corbit, Kevin. anti-BBS5 (14569-1-AP) marks the ciliary membrane and basal bodies of Human hTERT-RPE1 cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          BBS5 Antibody in Immunocytochemistry (ICC/IF)
          BBS5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BBS5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BBS5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BBS5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BBS5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BBS5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BBS5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BBS5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BBS5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BBS5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          BBS5 Antibody in Western Blot (WB)
          BBS5 Antibody in Western Blot (WB)
          BBS5 Antibody in Western Blot (WB)
          BBS5 Antibody in Western Blot (WB)
          BBS5 Antibody in Immunoprecipitation (IP)
          BBS5 Antibody in Immunoprecipitation (IP)

          Product Details

          14569-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:200-1:1,000
          View 13 publications 13 publications

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:10-1:100
          View 18 publications 18 publications

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          BBS5 Fusion Protein Ag6153 (1-341 aa encoded by BC044593)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.21 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MSVLDALWE DRDVRFDLSA QQMKTRPGEV LIDCLDSIED TKGNNGDRGR LLVTNLRILW HSLALSRVNV SVGYNCILNI TTRTANSKLR GQTEALYILT KCNSTRFEFI FTNLVPGSPR LFTSVMAVHR AYETSKMYRD FKLRSALIQN KQLRLLPQEH VYDKINGVWN LSSDQGNLGT FFITNVRIVW HANMNDSFNV SIPYLQIRSI KIRDSKFGLA LVIESSQQSG GYVLGFKIDP VEKLQESVKE INSLHKVYSA SPIFGVDYEM EEKPQPLEAL TVEQIQDDVE IDSDGHTDAF VAYFADGNKQ QDREPVFSEE LGLAIEKLKD GFTLQGLWEV MS (1-341 aa encoded by BC044593)

          Target Information

          The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for BBSome complex ciliary localization but not for the proper complex assembly.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Bardet-Biedl syndrome 5 homolog; Bardet-Biedl syndrome 5 protein; Bardet-Biedl syndrome 5 protein homolog; BBSome complex member BBS5; novel DUF1448 protein

          View more View less

          Gene Aliases: 1700049I01Rik; 2700023J09Rik; BBS5

          View more View less

          UniProt ID: (Human) Q8N3I7, (Mouse) Q9CZQ9

          View more View less

          Entrez Gene ID: (Human) 129880, (Mouse) 72569, (Rat) 362142

          View more View less

          Function(s)
          RNA polymerase II repressing transcription factor binding protein binding phosphatidylinositol-3-phosphate binding molecular_function
          Process(es)
          transport protein transport cell projection organization cilium assembly intracellular transport heart looping visual perception melanosome transport motile cilium assembly response to stimulus biological_process
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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