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Proteintech
BBS6 Polyclonal Antibody
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Product Details
13078-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BBS6 Fusion Protein Ag3785 (223-570 aa encoded by BC028973)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SEVQLMRLL PIKKSTALKV ALFCTTLSGD TSDTGEGTVV VSYGVSLENA VLDQLLNLGR QLISDHVDLV LCQKVIHPSL KQFLNMHRII AIDRIGVTLM EPLTKMTGTQ PIGSLGSICP NSYGSVKDVC TAKFGSKHFF HLIPNEATIC SLLLCNRNDT AWDELKLTCQ TALHVLQLTL KEPWALLGGG CTETHLAAYI RHKTHNDPES ILKDDECTQT ELQLIAEAFC SALESVVGSL EHDGGEILTD MKYGHLWSVQ ADSPCVANWP DLLSQCGCGL YNSQEELNWS FLRSTCRPFV PQSCLPHEAV VSASNLTLDC LTAKLSGLQV AVETANLILD LSYVIEDKN (223-570 aa encoded by BC028973)
Target Information
Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bardet-Biedl syndrome 6 protein; McKusick-Kaufman syndrome protein; McKusick-Kaufman syndrome protein; MKKS protein; McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin; Molecular chaperone MKKS; Protein Bbs6 homolog
Gene Aliases: 1300013E18Rik; AI463362; AI957237; BBS6; HMCS; KMS; MKKS; MKS
UniProt ID: (Human) Q9NPJ1, (Mouse) Q9JI70
Entrez Gene ID: (Human) 8195, (Mouse) 59030, (Rat) 311456
protein folding
spermatid development
sensory perception of smell
negative regulation of gene expression
artery smooth muscle contraction
striatum development
hippocampus development
cerebral cortex development
negative regulation of actin filament polymerization
leptin-mediated signaling pathway
negative regulation of GTPase activity
nonmotile primary cilium assembly
social behavior
negative regulation of appetite by leptin-mediated signaling pathway
positive regulation of multicellular organism growth
vasodilation
cilium assembly
response to leptin
photoreceptor cell maintenance
negative regulation of blood pressure
brain morphogenesis
detection of mechanical stimulus involved in sensory perception of sound
chaperone-mediated protein complex assembly
cartilage development
regulation of stress fiber assembly
cilium morphogenesis
regulation of cilium beat frequency involved in ciliary motility
face development
heart looping
determination of left/right symmetry
heart development
visual perception
gonad development
melanosome transport
fat cell differentiation
intracellular transport
pigment granule aggregation in cell center
convergent extension involved in gastrulation
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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