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Proteintech
BBS8 Polyclonal Antibody
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Product Details
12505-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BBS8 Fusion Protein Ag3186 (200-531 aa encoded by BC026351)
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Western blot analysis using this antibody detected a major band around 60 kDa in lung tissue.
Immunogen sequence: HLEDVVLHL GIYPFLLRNK NHIEKNALDL AALSTEHSQY KDWWWKVQIG KCYYRLGMYR EAEKQFKSAL KQQEMVDTFL YLAKVYVSLD QPVTALNLFK QGLDKFPGEV TLLCGIARIY EEMNNMSSAA EYYKEVLKQD NTHVEAIACI GSNHFYSDQP EIALRFYRRL LQMGIYNGQL FNNLGLCCFY AQQYDMTLTS FERALSLAEN EEEAADVWYN LGHVAVGIGD TNLAHQCFRL ALVNNNNHAE AYNNLAVLEM RKGHVEQARA LLQTASSLAP HMYEPHFNFA TISDKIGDLQ RSYVAAQKSE AAFPDHVDTQ HLIKQLRQHF AML (200-531 aa encoded by BC026351)
Target Information
This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. Alternate transcriptional splice variants have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bardet-Biedl syndrome 8 protein; Bardet-Biedl syndrome 8 protein homolog; Bardet-Biedl syndrome type 8; Tetratricopeptide repeat protein 8; TPR repeat protein 8
Gene Aliases: 0610012F22Rik; AV001447; BBS8; RP51; TTC8
UniProt ID: (Human) Q8TAM2, (Mouse) Q8VD72
Entrez Gene ID: (Human) 123016, (Rat) 299246, (Mouse) 76260
axon guidance
sensory perception of smell
biological_process
olfactory bulb development
regulation of protein localization
nonmotile primary cilium assembly
multicellular organism growth
cilium assembly
fat cell differentiation
establishment of anatomical structure orientation
regulation of stress fiber assembly
camera-type eye photoreceptor cell differentiation
renal tubule development
protein transport
sensory processing
transport
cell projection organization
negative regulation of GTPase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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