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Invitrogen
BCAR3 Polyclonal Antibody
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Product Details
PA5-34425
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 16 amino acid synthetic peptide near the amino terminus of human BCAR3
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2551777
Product Specific Information
A suggested positive control is Hela cell lysate.
PA5-34425 can be used with blocking peptide PEP-1467.
Target Information
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BCAR3 adapter protein, NSP family member; Breast cancer anti-estrogen resistance protein 3; Breast cancer anti-estrogen resistance protein 3 homolog; breast cancer antiestrogen resistance 3 protein; dJ1033H22.2 (breast cancer anti-estrogen resistance 3); KIAA0554; Novel SH2-containing protein 2; OTTHUMP00000011961; p130Cas-binding protein AND-34; SH2 domain-containing protein 3B
Gene Aliases: AI131758; AND-34; And34; BCAR3; NSP2; SH2D3B; UNQ271/PRO308
UniProt ID: (Human) O75815, (Mouse) Q9QZK2, (Rat) D3ZAZ5
Entrez Gene ID: (Human) 8412, (Mouse) 29815, (Rat) 310838
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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