Proteintech

BCL9 Polyclonal Antibody

BCL9 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 7

BCL9 Antibody (22947-1-AP) in ICC/IF

Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using 22947-1-AP (BCL9 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

BCL9 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

Product Details

22947-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 3 publications 3 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:20-1:200

View 1 publication 1 publication

Immunoprecipitation (IP)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

BCL9 Fusion Protein Ag19158 (8-340 aa encoded by BC116451)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.44 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: VRSSPSGNT QSSPKSKQEV MVRPPTVMSP SGNPQLDSKF SNQGKQGGSA SQSQPSPCDS KSGGHTPKAL PGPGGSMGLK NGAGNGAKGK GKRERSISAD SFDQRDPGTP NDDSDIKECN SADHIKSQDS QHTPHSMTPS NATAPRSSTP SHGQTTATEP TPAQKTPAKV VYVFSTEMAN KAAEAVLKGQ VETIVSFHIQ NISNNKTERS TAPLNTQISA LRNDPKPLPQ QPPAPANQDQ NSSQNTRLQP TPPIPAPAPK PAAPPRPLDR ESPGVENKLI PSVGSPASST PLPPDGTGPN STPNNRAVTP VSQGSNSSSA DPKAPPPPPV SSGE (8-340 aa encoded by BC116451)

Target Information

BCL9 is involved in signal transduction through the Wnt pathway. It promotes beta-catenin's transcriptional activity. BCL9 is associated with B-cell acute lymphoblastic leukemia. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Discovery of 2-(isoxazol-5-yl)phenyl 3,4-dihydroxybenzoate as a potential inhibitor for the Wnt/β-catenin pathway.

Bioorganic chemistry

Dong Y,Liu M,Mao Y,Wu S,Wen J,Lu J,Yang Y,Ruan S,Li L,Liu X,Zhang J,Liao S,Dong L

Tue Nov 01 00:00:00 UTC 2022

Exosomal AFAP1-AS1 binds to microRNA-15a-5p to promote the proliferation, migration, and invasion of ectopic endometrial stromal cells in endometriosis.

Reproductive biology and endocrinology : RB&E

Wang X,Zhang M,Jiang L,Fang X,Zhang T

Thu May 05 00:00:00 UTC 2022

Exosomal AFAP1-AS1 binds to microRNA-15a-5p to promote the proliferation, migration, and invasion of ectopic endometrial stromal cells in endometriosis.

Reproductive biology and endocrinology : RB&E

Wang X,Zhang M,Jiang L,Fang X,Zhang T

Thu May 05 00:00:00 UTC 2022

Exosomal AFAP1-AS1 binds to microRNA-15a-5p to promote the proliferation, migration, and invasion of ectopic endometrial stromal cells in endometriosis.

Reproductive biology and endocrinology : RB&E

Wang X,Zhang M,Jiang L,Fang X,Zhang T

Thu May 05 00:00:00 UTC 2022

Exosomal AFAP1-AS1 binds to microRNA-15a-5p to promote the proliferation, migration, and invasion of ectopic endometrial stromal cells in endometriosis.

Reproductive biology and endocrinology : RB&E

Wang X,Zhang M,Jiang L,Fang X,Zhang T

Thu May 05 00:00:00 UTC 2022

USP9X-mediated deubiquitination of B-cell CLL/lymphoma 9 potentiates Wnt signaling and promotes breast carcinogenesis.

The Journal of biological chemistry

Shang Z,Zhao J,Zhang Q,Cao C,Tian S,Zhang K,Liu L,Shi L,Yu N,Yang S

Fri Jun 21 00:00:00 UTC 2019

USP9X-mediated deubiquitination of B-cell CLL/lymphoma 9 potentiates Wnt signaling and promotes breast carcinogenesis.

The Journal of biological chemistry

Shang Z,Zhao J,Zhang Q,Cao C,Tian S,Zhang K,Liu L,Shi L,Yu N,Yang S

Fri Jun 21 00:00:00 UTC 2019

USP9X-mediated deubiquitination of B-cell CLL/lymphoma 9 potentiates Wnt signaling and promotes breast carcinogenesis.

The Journal of biological chemistry

Shang Z,Zhao J,Zhang Q,Cao C,Tian S,Zhang K,Liu L,Shi L,Yu N,Yang S

Fri Jun 21 00:00:00 UTC 2019

Bioinformatics

Protein Aliases: B-cell CLL/lymphoma 9 protein; B-cell lymphoma 9 protein; bcl-9; Protein legless homolog

View more View less

Gene Aliases: BCL9; LGS

View more View less

UniProt ID: (Human) O00512

View more View less

Entrez Gene ID: (Human) 607

View more View less

Function(s)

protein binding beta-catenin binding

Process(es)

myotube differentiation involved in skeletal muscle regeneration regulation of transforming growth factor beta receptor signaling pathway somatic stem cell population maintenance skeletal muscle cell differentiation positive regulation of transcription from RNA polymerase II promoter canonical Wnt signaling pathway beta-catenin-TCF complex assembly

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

BCL9 Polyclonal Antibody

BCL9 Antibody (22947-1-AP) in ICC/IF

Product Details

22947-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!