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Abnova
BCL9 Monoclonal Antibody (2D4)
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Product Details
H00000607-M01
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
2D4
Immunogen
BCL9 (NP_004317, 1036 a.a. approximately 1135 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: DDDSPPARSP NLPSMNNMPG MGINTQNPRI SGPNPVVPMP TLSPMGMTQP LSHSNQMPSP NAVGPNIPPH GVPMGPGLMS HNPIMGHGSQ EPPMVPQGRM
Target Information
BCL9 is involved in signal transduction through the Wnt pathway. It promotes beta-catenin's transcriptional activity. BCL9 is associated with B-cell acute lymphoblastic leukemia. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B-cell CLL/lymphoma 9 protein; B-cell lymphoma 9 protein; bcl-9; Protein legless homolog
Gene Aliases: BCL9; LGS
UniProt ID: (Human) O00512
Entrez Gene ID: (Human) 607
myotube differentiation involved in skeletal muscle regeneration
regulation of transforming growth factor beta receptor signaling pathway
somatic stem cell population maintenance
skeletal muscle cell differentiation
positive regulation of transcription from RNA polymerase II promoter
canonical Wnt signaling pathway
beta-catenin-TCF complex assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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