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Proteintech
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Immunogen sequence: MGRLDGKVII LTAAAQGIGQ AAALAFAREG AKVIATDINE SKLQELEKYP GIQTRVLDVT KKKQIDQFAN EVERLDVLFN VAGFVHHGTV LDCEEKDWDF SMNLNVRSMY LMIKAFLPKM LAQKSGNIIN MSSVASSVKG VVNRCVYSTT KAAVIGLTKS VAADFIQQGI RCNCVCPGTV DTPSLQERIQ ARGNPEEARN DFLKRQKTGR FATAEEIAML CVYLASDEST YVTGNPVIID GGWSL
Dehydrogenase that mediates the formation of 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron assimilation and homeostasis. Plays a role in susceptibility to bacterial infection by providing an assimilable source of iron that is exploited by pathogenic bacteria. Also acts as a 3-hydroxybutyrate dehydrogenase (PubMed:16380372). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: (R)-beta-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase type 2; 4-oxo-L-proline reductase; dehydrogenase/reductase (SDR family) member 6; Dehydrogenase/reductase SDR family member 6; FLJ13261; Oxidoreductase UCPA; R-beta-hydroxybutyrate dehydrogenase; Short chain dehydrogenase/reductase family 15C member 1; short chain dehydrogenase/reductase family 15C, member 1
Gene Aliases: BDH2; DHRS6; EFA6R; PRO20933; SDR15C1; UCPA-OR; UNQ6308; UNQ6308/PRO20933
UniProt ID: (Human) Q9BUT1
Entrez Gene ID: (Human) 56898
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