Invitrogen

BDKRB2 Polyclonal Antibody

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BDKRB2 Antibody (720288) in WB

Western blot analysis was performed on whole cell extracts (30 µg lysate) of Mouse Cerebellum (Lane1), Rat Brain (Lane2), Mouse Brain (Lane3), Neuro-2a (Lane4), SH SY5Y (Lane5). The blots were probed with BDKRB2 Rabbit Polyclonal Antibody (Product # 720288, 1-2 µg/mL) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.4 µg/mL, 1:2500 dilution). A 40 kDa band corresponding to BDKRB2 was observed across cell lines tested. Known quantity of protein sam... View More

BDKRB2 Antibody in Western Blot, Immunoprecipitation (WB, IP)

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Product Details

720288

Applications

Tested Dilution

Publications

Western Blot (WB)

1-2 µg/mL

View 2 publications 2 publications

Immunoprecipitation (IP)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide corresponding to Human Bdkrb2 (aa 377-391)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with 0.1% BSA, 30% glycerol

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2633240

Product Specific Information

These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature.

This antibody is predicted to react with Rat, Mouse, Pig and Cat.

Target Information

Bradykinin B2 receptor (BDKRB2) expression has been reported in blood, brain, eye, kidney, liver, lung, prostate, skin, small intestine, synovium, uterus, and vessel. ESTs have been isolated from colon, connective tissue, heart, heart/melanocyte/uterus, and kidney libraries. It is associated with G-proteins that activate a phosphatidylinositol-calcium second messenger system.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Rutin protects against gamma-irradiation and malathion-induced oxidative stress and inflammation through regulation of mir-129-3p, mir-200C-3p, and mir-210 gene expressions in rats' kidney.

Environmental science and pollution research international

Ismail AFM,Salem AA,Eassawy MMT

720288 was used in Western Blot to demonstrate that rutin treatment regulated the biochemical parameters, the oxidative stress, the antioxidant status, and the inflammatory responses due to the down-regulation of the renal NF-κB p65 protein expression.

Thu Jun 01 00:00:00 UTC 2023

Heteromerization fingerprints between bradykinin B2 and thromboxane TP receptors in native cells.

PloS one

Dagher OK,Jaffa MA,Habib A,Ziyadeh FN,Jaffa AA

720288 was used in Western Blotting to determine the effect of B2R-TP heterodimerisation on the coregulation of B2R and TP.

Wed Jan 22 00:00:00 UTC 2020

Heteromerization fingerprints between bradykinin B2 and thromboxane TP receptors in native cells.

PloS one

Dagher OK,Jaffa MA,Habib A,Ziyadeh FN,Jaffa AA

720288 was used in Western Blotting to determine the effect of B2R-TP heterodimerisation on the coregulation of B2R and TP.

Wed Jan 22 00:00:00 UTC 2020

Bioinformatics

Protein Aliases: B2 bradykinin receptor; B2R; BK-2 receptor; BK-2R; BK-2Rs; bradykinin receptor, beta 2; DKFZp686O088; kinin B2

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Gene Aliases: B(2); B2; B2BKR; B2BRA; B2R; BDKRB2; BK-2; BK2; BK2R; BKR2; BRB2

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UniProt ID: (Human) P30411, (Mouse) P32299, (Rat) P25023

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Entrez Gene ID: (Human) 624, (Mouse) 12062, (Rat) 25245

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Function(s)

protease binding phosphatidylinositol phospholipase C activity bradykinin receptor activity protein binding beta-2 adrenergic receptor binding type 1 angiotensin receptor binding protein heterodimerization activity signal transducer activity G-protein coupled receptor activity

Process(es)

acute inflammatory response to antigenic stimulus smooth muscle contraction response to stress signal transduction G-protein coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration negative regulation of cell proliferation response to salt stress negative regulation of peptidyl-serine phosphorylation maintenance of blood-brain barrier vasoconstriction vasodilation negative regulation of blood pressure arachidonic acid secretion negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator inflammatory response cell surface receptor signaling pathway transmembrane receptor protein tyrosine kinase signaling pathway blood circulation regulation of vasoconstriction response to drug regulation of vascular permeability cellular response to hypoxia sensory perception of pain

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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BDKRB2 Polyclonal Antibody

BDKRB2 Antibody (720288) in WB

Product Details

720288

Western Blot (WB)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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