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Product Details
20931-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BEND5 Fusion Protein Ag14930 (71-421 aa encoded by BC007932)
Conjugate
Form
Liquid
Concentration
0.45 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: ILALAEDKS DLENSVMQKK IKIPKLSLNH VEEDGEVKDY GEEDLQLRHI KRPEGRKPSE VAHKSIEAVV ARLEKQNGLS LGHSTCPEEV FVEASPGTED MDSLEDAVVP RALYEELLRN YQQQQEEMRH LQQELERTRR QLVQQAKKLK EYGALVSEMK ELRDLNRRLQ DVLLLRLGSG PAIDLEKVKS ECLEPEPELR STFSEEANTS SYYPAPAPVM DKYILDNGKV HLGSGIWVDE EKWHQLQVTQ GDSKYTKNLA VMIWGTDVLK NRSVTGVATK KKKDAVPKPP LSPHKLSIVR ECLYDRIAQE TVDETEIAQR LSKVNKYICE KIMDINKSCK NEERREAKYN LQ (71-421 aa encoded by BC007932)
Target Information
C1orf165, also known as CFAP299 (Cilia and Flagella Associated Protein 299), is located on chromosome 1 and encodes a protein that is implicated in ciliary function and structure. CFAP299 is essential for the proper assembly and motility of cilia and flagella, structures that are vital for various cellular processes, including cell motility, fluid movement, and signal transduction. Mutations in CFAP299 have been linked to primary ciliary dyskinesia (PCD), which is characterized by chronic respiratory tract infections, abnormal positioning of internal organs (situs inversus), and infertility due to defective cilia and flagella movement. The protein has been shown to interact with other ciliary proteins and play a role in the regulation of dynein arms and microtubule structures necessary for ciliary beating.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BEN domain-containing protein 5
Gene Aliases: 2310026E23Rik; BEND5; C1orf165
UniProt ID: (Human) Q7L4P6, (Mouse) Q8C6D4
Entrez Gene ID: (Human) 79656, (Mouse) 67621
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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