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Product Details
25438-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BFSP2 Fusion Protein Ag22073 (1-225 aa encoded by BC113518)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSERRVVVD LPTSASSSMP LQRRRASFRG PRSSSSLESP PASRTNAMSG LVRAPGVYVG TAPSGCIGGL GARVTRRALG ISSVFLQGLR SSGLATVPAP GLERDHGAVE DLGGCLVEYM AKVHALEQVS QELETQLRMH LESKATRSGN WGALRASWAS SCQQVGEAVL ENARLMLQTE TIQAGADDFK ERYENEQPFR KAAEEEINSL YKVIDEANLT KMDLES (1-225 aa encoded by B C113518)
Target Information
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 49 kDa cytoskeletal protein; beaded filament protein CP49; Beaded filament structural protein 2; beaded filament structural protein 2, phakinin; bfps2, Cytoskeletal protein, 49-kD; CP47; CP49; Lens fiber cell beaded filament protein CP 47; Lens fiber cell beaded filament protein CP 49; Lens intermediate filament-like light; LIFL-L; MGC142078; MGC142080; Phakinin
Gene Aliases: AI448593; BFSP2; CP47; CP49; CTRCT12; LIFL-L; PHAKOSIN
UniProt ID: (Human) Q13515, (Rat) D3ZER2, (Mouse) Q6NVD9
Entrez Gene ID: (Human) 8419, (Rat) 501046, (Mouse) 107993
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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