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Invitrogen
BHLHB5 Polyclonal Antibody
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BHLHB5 Antibody (PA5-24711) in IHC (P)
Immunohistochemistry analysis of BHLHB5 in formalin fixed and paraffin embedded human brain tissue. Samples were incubated with BHLHB5 polyclonal antibody (Product # PA5-24711) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-24711
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 236-264 amino acids from the central region of human BHLHB5
Conjugate
Form
Liquid
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2542211
Product Specific Information
This antibody is predicted to react with chicken and mouse based on sequence homology.
Target Information
BHLHB5 inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. BHLHB5 despite the presence of an intact basic domain, does not bind to DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: basic helix-loop-helix domain containing, class B, 5; basic helix-loop-helix family, member e22; bHLHb5; bHLHe22; Class B basic helix-loop-helix protein 5; Class E basic helix-loop-helix protein 22; trinucleotide repeat containing 20; Trinucleotide repeat-containing gene 20 protein
Gene Aliases: Beta3; BHLHB5; BHLHE22; CAGL85; TNRC20
UniProt ID: (Human) Q8NFJ8
Entrez Gene ID: (Human) 27319
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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