Product References
Mutation in Smek2 regulating hepatic glucose metabolism causes hypersarcosinemia and hyperhomocysteinemia in rats.
Scientific reports
Tanaka Y,Kawano M,Nakashima S,Yamaguchi C,Asahina M,Sakamoto M,Shirouchi B,Tashiro K,Imaizumi K,Sato M
Tue Feb 21 00:00:00 UTC 2023
In ovo injection of betaine promotes adrenal steroidogenesis in pre-hatched chicken fetuses.
Poultry science
Abobaker H,Omer NA,Hu Y,Idriss AA,Zhao R
Wed Jun 01 00:00:00 UTC 2022
mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis.
Molecular cell
Villa E,Sahu U,O'Hara BP,Ali ES,Helmin KA,Asara JM,Gao P,Singer BD,Ben-Sahra I
Thu May 20 00:00:00 UTC 2021
The hepatic compensatory response to elevated systemic sulfide promotes diabetes.
Cell reports
Carter RN,Gibbins MTG,Barrios-Llerena ME,Wilkie SE,Freddolino PL,Libiad M,Vitvitsky V,Emerson B,Le Bihan T,Brice M,Su H,Denham SG,Homer NZM,Mc Fadden C,Tailleux A,Faresse N,Sulpice T,Briand F,Gillingwater T,Ahn KH,Singha S,McMaster C,Hartley RC,Staels B,Gray GA,Finch AJ,Selman C,Banerjee R,Morton NM
Tue Nov 09 00:00:00 UTC 2021
Chronopharmacological targeting of Rev-erbα by puerarin alleviates hyperhomocysteinemia in mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chen M,Zhou C,Xu H,Zhang T,Wu B
Fri May 01 00:00:00 UTC 2020
Maternal betaine supplementation decreases hepatic cholesterol deposition in chicken offspring with epigenetic modulation of SREBP2 and CYP7A1 genes.
Poultry science
Hu Y,Feng Y,Ding Z,Lv L,Sui Y,Sun Q,Abobaker H,Cai D,Zhao R
Mon Jun 01 00:00:00 UTC 2020
Transgenerational Inheritance of Betaine-Induced Epigenetic Alterations in Estrogen-Responsive IGF-2/IGFBP2 Genes in Rat Hippocampus.
Molecular nutrition & food research
Yang Y,Jiang W,Yang S,Qi F,Zhao R
Wed Apr 01 00:00:00 UTC 2020
Grandmaternal betaine supplementation enhances hepatic IGF2 expression in F2 rat offspring through modification of promoter DNA methylation.
Journal of the science of food and agriculture
Yang S,Zhao N,Sun B,Yang Y,Hu Y,Zhao R
Sun Mar 15 00:00:00 UTC 2020
Dietary betaine improves egg-laying rate in hens through hypomethylation and glucocorticoid receptor-mediated activation of hepatic lipogenesis-related genes.
Poultry science
Omer NA,Hu Y,Idriss AA,Abobaker H,Hou Z,Yang S,Ma W,Zhao R
Mon Jun 01 00:00:00 UTC 2020
Homocysteine impairs porcine oocyte quality via deregulation of one-carbon metabolism and hypermethylation of mitochondrial DNA†.
Biology of reproduction
Jia L,Zeng Y,Hu Y,Liu J,Yin C,Niu Y,Wang C,Li J,Jia Y,Hong J,Zhao R
Mon Apr 01 00:00:00 UTC 2019
Homocysteine impairs porcine oocyte quality via deregulation of one-carbon metabolism and hypermethylation of mitochondrial DNA†.
Biology of reproduction
Jia L,Zeng Y,Hu Y,Liu J,Yin C,Niu Y,Wang C,Li J,Jia Y,Hong J,Zhao R
Mon Apr 01 00:00:00 UTC 2019
DNA Hypomethylation of GR Promoters is Associated with GR Activation and BDNF/AKT/ERK1/2-Induced Hippocampal Neurogenesis in Mice Derived From Folic-Acid-Supplemented Dams.
Molecular nutrition & food research
Yang Y,Yang S,Liu J,Feng Y,Qi F,Zhao R
Sat Jun 01 00:00:00 UTC 2019
Significant Down-Regulation of Urea Cycle Generates Clinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion.
Journal of proteome research
Cao Y,Ding W,Zhang J,Gao Q,Yang H,Cao W,Wang Z,Fang L,Du R
Fri May 03 00:00:00 UTC 2019
Significant Down-Regulation of Urea Cycle Generates Clinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion.
Journal of proteome research
Cao Y,Ding W,Zhang J,Gao Q,Yang H,Cao W,Wang Z,Fang L,Du R
Fri May 03 00:00:00 UTC 2019
Dietary betaine activates hepatic VTGII expression in laying hens associated with hypomethylation of GR gene promoter and enhanced GR expression.
Journal of animal science and biotechnology
Omer NA,Hu Y,Hu Y,Idriss AA,Abobaker H,Hou Z,Dong H,Zhao R
Fri Mar 11 00:00:00 UTC 2022
Maternal betaine supplementation attenuates glucocorticoid-induced hepatic lipid accumulation through epigenetic modification in adult offspring rats.
The Journal of nutritional biochemistry
Zhao N,Yang S,Jia Y,Sun B,He B,Zhao R
Sun Apr 01 00:00:00 UTC 2018
Maternal betaine supplementation attenuates glucocorticoid-induced hepatic lipid accumulation through epigenetic modification in adult offspring rats.
The Journal of nutritional biochemistry
Zhao N,Yang S,Jia Y,Sun B,He B,Zhao R
Sun Apr 01 00:00:00 UTC 2018
Mitotically Stable Modification of DNA Methylation in IGF2/H19 Imprinting Control Region Is Associated with Activated Hepatic IGF2 Expression in Offspring Rats from Betaine-Supplemented Dams.
Journal of agricultural and food chemistry
Yang S,Zhao N,Yang Y,Hu Y,Dong H,Zhao R
Wed Mar 21 00:00:00 UTC 2018
Mitotically Stable Modification of DNA Methylation in IGF2/H19 Imprinting Control Region Is Associated with Activated Hepatic IGF2 Expression in Offspring Rats from Betaine-Supplemented Dams.
Journal of agricultural and food chemistry
Yang S,Zhao N,Yang Y,Hu Y,Dong H,Zhao R
Wed Mar 21 00:00:00 UTC 2018
Corticosterone-Induced Lipogenesis Activation and Lipophagy Inhibition in Chicken Liver Are Alleviated by Maternal Betaine Supplementation.
The Journal of nutrition
Hu Y,Sun Q,Hu Y,Hou Z,Zong Y,Omer NA,Abobaker H,Zhao R
Thu Mar 01 00:00:00 UTC 2018
Corticosterone-Induced Lipogenesis Activation and Lipophagy Inhibition in Chicken Liver Are Alleviated by Maternal Betaine Supplementation.
The Journal of nutrition
Hu Y,Sun Q,Hu Y,Hou Z,Zong Y,Omer NA,Abobaker H,Zhao R
Thu Mar 01 00:00:00 UTC 2018
Maternal betaine administration modulates hepatic type 1 iodothyronine deiodinase (Dio1) expression in chicken offspring through epigenetic modifications.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
Hou Z,Sun Q,Hu Y,Yang S,Zong Y,Zhao R
Sun Apr 01 00:00:00 UTC 2018
Maternal betaine administration modulates hepatic type 1 iodothyronine deiodinase (Dio1) expression in chicken offspring through epigenetic modifications.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
Hou Z,Sun Q,Hu Y,Yang S,Zong Y,Zhao R
Sun Apr 01 00:00:00 UTC 2018
Dietary betaine supplementation in hens modulates hypothalamic expression of cholesterol metabolic genes in F1 cockerels through modification of DNA methylation.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
Idriss AA,Hu Y,Hou Z,Hu Y,Sun Q,Omer NA,Abobaker H,Ni Y,Zhao R
Thu Mar 01 00:00:00 UTC 2018
Dietary betaine supplementation in hens modulates hypothalamic expression of cholesterol metabolic genes in F1 cockerels through modification of DNA methylation.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
Idriss AA,Hu Y,Hou Z,Hu Y,Sun Q,Omer NA,Abobaker H,Ni Y,Zhao R
Thu Mar 01 00:00:00 UTC 2018
Maternal betaine supplementation in rats induces intergenerational changes in hepatic IGF-1 expression and DNA methylation.
Molecular nutrition & food research
Zhao N,Yang S,Hu Y,Dong H,Zhao R
Tue Aug 01 00:00:00 UTC 2017
Maternal betaine supplementation in rats induces intergenerational changes in hepatic IGF-1 expression and DNA methylation.
Molecular nutrition & food research
Zhao N,Yang S,Hu Y,Dong H,Zhao R
Tue Aug 01 00:00:00 UTC 2017
Prenatal betaine exposure modulates hypothalamic expression of cholesterol metabolic genes in cockerels through modifications of DNA methylation.
Poultry science
Idriss AA,Hu Y,Sun Q,Jia L,Jia Y,Omer NA,Abobaker H,Zhao R
Thu Jun 01 00:00:00 UTC 2017
Prenatal betaine exposure modulates hypothalamic expression of cholesterol metabolic genes in cockerels through modifications of DNA methylation.
Poultry science
Idriss AA,Hu Y,Sun Q,Jia L,Jia Y,Omer NA,Abobaker H,Zhao R
Thu Jun 01 00:00:00 UTC 2017
Downregulation of miR-150 Expression by DNA Hypermethylation Is Associated with High 2-Hydroxy-(4-methylthio)butanoic Acid-Induced Hepatic Cholesterol Accumulation in Nursery Piglets.
Journal of agricultural and food chemistry
Jia Y,Ling M,Zhang L,Jiang S,Sha Y,Zhao R
Wed Oct 12 00:00:00 UTC 2016
Downregulation of miR-150 Expression by DNA Hypermethylation Is Associated with High 2-Hydroxy-(4-methylthio)butanoic Acid-Induced Hepatic Cholesterol Accumulation in Nursery Piglets.
Journal of agricultural and food chemistry
Jia Y,Ling M,Zhang L,Jiang S,Sha Y,Zhao R
Wed Oct 12 00:00:00 UTC 2016
Folate deprivation induces cell cycle arrest at G0/G1 phase and apoptosis in hippocampal neuron cells through down-regulation of IGF-1 signaling pathway.
The international journal of biochemistry & cell biology
Yang Y,Li X,Sun Q,He B,Jia Y,Cai D,Zhao R
Sat Oct 01 00:00:00 UTC 2016
Folate deprivation induces cell cycle arrest at G0/G1 phase and apoptosis in hippocampal neuron cells through down-regulation of IGF-1 signaling pathway.
The international journal of biochemistry & cell biology
Yang Y,Li X,Sun Q,He B,Jia Y,Cai D,Zhao R
Sat Oct 01 00:00:00 UTC 2016
Identification of Organ-Enriched Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics of Blood in Acetaminophen- and Carbon-Tetrachloride-Treated Mouse Models and Acetaminophen Overdose Patients.
Journal of proteome research
Qin S,Zhou Y,Gray L,Kusebauch U,McEvoy L,Antoine DJ,Hampson L,Park KB,Campbell D,Caballero J,Glusman G,Yan X,Kim TK,Yuan Y,Wang K,Rowen L,Moritz RL,Omenn GS,Pirmohamed M,Hood L
Fri Oct 07 00:00:00 UTC 2016
Identification of Organ-Enriched Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics of Blood in Acetaminophen- and Carbon-Tetrachloride-Treated Mouse Models and Acetaminophen Overdose Patients.
Journal of proteome research
Qin S,Zhou Y,Gray L,Kusebauch U,McEvoy L,Antoine DJ,Hampson L,Park KB,Campbell D,Caballero J,Glusman G,Yan X,Kim TK,Yuan Y,Wang K,Rowen L,Moritz RL,Omenn GS,Pirmohamed M,Hood L
Fri Oct 07 00:00:00 UTC 2016
Identification of Organ-Enriched Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics of Blood in Acetaminophen- and Carbon-Tetrachloride-Treated Mouse Models and Acetaminophen Overdose Patients.
Journal of proteome research
Qin S,Zhou Y,Gray L,Kusebauch U,McEvoy L,Antoine DJ,Hampson L,Park KB,Campbell D,Caballero J,Glusman G,Yan X,Kim TK,Yuan Y,Wang K,Rowen L,Moritz RL,Omenn GS,Pirmohamed M,Hood L
Fri Oct 07 00:00:00 UTC 2016
Abnormally activated one-carbon metabolic pathway is associated with mtDNA hypermethylation and mitochondrial malfunction in the oocytes of polycystic gilt ovaries.
Scientific reports
Jia L,Li J,He B,Jia Y,Niu Y,Wang C,Zhao R
Wed Jan 13 00:00:00 UTC 2016
Abnormally activated one-carbon metabolic pathway is associated with mtDNA hypermethylation and mitochondrial malfunction in the oocytes of polycystic gilt ovaries.
Scientific reports
Jia L,Li J,He B,Jia Y,Niu Y,Wang C,Zhao R
Wed Jan 13 00:00:00 UTC 2016
Maternal Betaine Supplementation throughout Gestation and Lactation Modifies Hepatic Cholesterol Metabolic Genes in Weaning Piglets via AMPK/LXR-Mediated Pathway and Histone Modification.
Nutrients
Cai D,Yuan M,Liu H,Pan S,Ma W,Hong J,Zhao R
Tue Oct 18 00:00:00 UTC 2016
Maternal Betaine Supplementation during Gestation Enhances Expression of mtDNA-Encoded Genes through D-Loop DNA Hypomethylation in the Skeletal Muscle of Newborn Piglets.
Journal of agricultural and food chemistry
Jia Y,Song H,Gao G,Cai D,Yang X,Zhao R
Wed Nov 25 00:00:00 UTC 2015
Maternal Betaine Supplementation during Gestation Enhances Expression of mtDNA-Encoded Genes through D-Loop DNA Hypomethylation in the Skeletal Muscle of Newborn Piglets.
Journal of agricultural and food chemistry
Jia Y,Song H,Gao G,Cai D,Yang X,Zhao R
Wed Nov 25 00:00:00 UTC 2015
Dietary betaine supplementation to gestational sows enhances hippocampal IGF2 expression in newborn piglets with modified DNA methylation of the differentially methylated regions.
European journal of nutrition
Li X,Sun Q,Li X,Cai D,Sui S,Jia Y,Song H,Zhao R
Thu Oct 01 00:00:00 UTC 2015
Dietary betaine supplementation to gestational sows enhances hippocampal IGF2 expression in newborn piglets with modified DNA methylation of the differentially methylated regions.
European journal of nutrition
Li X,Sun Q,Li X,Cai D,Sui S,Jia Y,Song H,Zhao R
Thu Oct 01 00:00:00 UTC 2015
In Ovo injection of betaine affects hepatic cholesterol metabolism through epigenetic gene regulation in newly hatched chicks.
PloS one
Hu Y,Sun Q,Li X,Wang M,Cai D,Li X,Zhao R
Thu Mar 31 00:00:00 UTC 2016
In Ovo injection of betaine affects hepatic cholesterol metabolism through epigenetic gene regulation in newly hatched chicks.
PloS one
Hu Y,Sun Q,Li X,Wang M,Cai D,Li X,Zhao R
Thu Mar 31 00:00:00 UTC 2016
Betaine supplementation in maternal diet modulates the epigenetic regulation of hepatic gluconeogenic genes in neonatal piglets.
PloS one
Cai D,Jia Y,Song H,Sui S,Lu J,Jiang Z,Zhao R
Thu Nov 12 00:00:00 UTC 2015
Betaine supplementation in maternal diet modulates the epigenetic regulation of hepatic gluconeogenic genes in neonatal piglets.
PloS one
Cai D,Jia Y,Song H,Sui S,Lu J,Jiang Z,Zhao R
Thu Nov 12 00:00:00 UTC 2015
Multifactorial comparative proteomic study of cytochrome P450 2E1 function in chronic alcohol administration.
PloS one
Wang Y,Kou Y,Wang X,Cederbaum A,Wang R
Tue Jan 20 00:00:00 UTC 2015
Multifactorial comparative proteomic study of cytochrome P450 2E1 function in chronic alcohol administration.
PloS one
Wang Y,Kou Y,Wang X,Cederbaum A,Wang R
Tue Jan 20 00:00:00 UTC 2015
