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Product Details
16351-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BHMT2 Fusion Protein Ag9558 (1-363 aa encoded by BC020665)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAPAGRPGA KKGILERLES GEVVIGDGSF LITLEKRGYV KAGLWTPEAV IEHPDAVRQL HMEFLRAGSN VMQTFTFSAS EDNMESKWED VNAAACDLAR EVAGKGDALV AGGICQTSIY KYQKDEARIK KLFRQQLEVF AWKNVDFLIA EYFEHVEEAV WAVEVLKESD RPVAVTMCIG PEGDMHDITP GECAVRLVKA GASIVGVNCR FGPDTSLKTM ELMKEGLEWA GLKAHLMVQP LGFHAPDCGK EGFVDLPEYP FGLESRVATR WDIQKYAREA YNLGVRYIGG CCGFEPYHIR AIAEELAPER GFLPPASEKH GSWGSGLDMH TKPWIRARAR REYWENLLPA SGRPFCPSLS KPDF (1-363 aa encoded by BC020665)
Target Information
Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Betaine--homocysteine S-methyltransferase 2; betaine-homocysteine methyltransferase 2; S-methylmethionine--homocysteine S-methyltransferase BHMT2; SMM-hcy methyltransferase
Gene Aliases: BHMT2; C81077; D13Ucla2
UniProt ID: (Human) Q9H2M3, (Mouse) Q91WS4, (Rat) Q68FT5
Entrez Gene ID: (Human) 23743, (Mouse) 64918, (Rat) 365972
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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