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Bethyl Laboratories
BIG1/ARFGEF1 Polyclonal Antibody
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BIG1/ARFGEF1 Antibody (A300-998A) in IHC (P)
Detection of human BIG1/ARFGEF1 by immunohistochemistry. Sample: FFPE section of human testicular seminoma. Antibody: Affinity purified rabbit anti-BIG1/ARFGEF1 (Product # A300-998A) (Lot 2) used at a dilution of 1:1,000 (1 µg/mL). Detection: DAB.
Product Details
A300-998A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 1800 and the C-terminus (residue 1849) of human brefeldin A-inhibited guanine nucleotide-exchange protein 1 (ADP-ribosylation factor guanine nucleotide-exchange factor 1).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Rat and Bovine
Target Information
The function of this protein remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP-ribosylation factor guanine nucleotide-exchange factor 1; ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited); BIG1; Brefeldin A-inhibited GEP 1; Brefeldin A-inhibited guanine nucleotide-exchange protein 1; DKFZP434L057; p200 ARF guanine nucleotide exchange factor; p200 ARF-GEP1
Gene Aliases: ARFGEF1; ARFGEP1; BIG1; D130059B05Rik; D730028O18Rik; P200
UniProt ID: (Human) Q9Y6D6, (Mouse) G3X9K3
Entrez Gene ID: (Human) 10565, (Mouse) 211673
exocytosis
Golgi organization
endomembrane system organization
protein transport
negative regulation of actin filament polymerization
neuron projection development
regulation of ARF protein signal transduction
negative regulation of GTPase activity
positive regulation of GTPase activity
positive regulation of protein kinase B signaling
positive regulation of protein glycosylation in Golgi
positive regulation of wound healing
regulation of establishment of cell polarity
transport
vesicle-mediated transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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