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Immunogen sequence: EDGRLVQFL LMNPANDGGQ WDMLVNIVEK YGVIPKKCFP ESYTTEATRR MNDILNHKMR EFCIRLRNLV HSGATKGEIS ATQDVMMEEI FRVVCICLGN PPETFTWEYR DKDKNYQKIG PITPLEFYRE HVKPLFNMED KICLVNDPRP QHKYNKLYTV EYLSNMVGGR KTLYNNQPID FLKKMVAASI KDGEAVWFGC DVGKHFNSKL GLSDMNLYDH ELVFGVSLKN MNKAERLTFG ESLMTHAMTF TAVSEKDDQD GAFTKWRVEN SWGEDHGHKG YLCMTDEWFS EYVYEVVVDR KHVPEEVLAV LEQEPIILPA WDPMGALAE (128-455 aa encoded by BC003616)
The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BH; Bleomycin hydrolase; BLM hydrolase; BMH
Gene Aliases: AI035728; BH; BLMH; BMH
UniProt ID: (Human) Q13867, (Mouse) Q8R016
Entrez Gene ID: (Human) 642, (Mouse) 104184, (Rat) 287552
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