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Proteintech
BLNK Polyclonal Antibody
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Product Details
10855-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BLNK Fusion Protein Ag1290 (1-456 aa encoded by BC018906)
Conjugate
Form
Liquid
Concentration
0.53 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MDKLNKITV PASQKLRQLQ KMVHDIKNNE GGIMNKIKKL KVKAPPSVPR RDYASESPAD EEQQWSDDFD SDYENPDEHS DSEMYVMPAE ENADDSYEPP PVEQETRPVH PALPFARGEY IDNRSSQRHS PPFSKTLPSK PSWPSEKARL TSTLPALTAL QKPQVPPKPK GLLEDEADYV VPVEDNDENY IHPTESSSPP PEKAPMVNRS TKPNSSTPAS PPGTASGRNS GAWETKSPPP AAPSPLPRAG KKPTTPLKTT PVASQQNASS VCEEKPIPAE RHRGSSHRQE AVQSPVFPPA QKQIHQKPIP LPRFTEGGNP TVDGPLPSFS SNSTISEQEA GVLCKPWYAG ACDRKSAEEA LHRSNKDGSF LIRKSSGHDS KQPYTLVVFF NKRVYNIPVR FIEATKQYAL GRKKNGEEYF GSVAEIIRNH QHSPLVLIDS QNNTKDSTRL KYAVKVS (1-456 aa encoded by BC018906)
Target Information
B cell linker protein (Blnk) is a protein encoded by the Blnk gene located on chromosome 10 in humans. It is also known as SLP 65 (Src homology 2 domain-containing leukocyte protein of 65 kDa). It derives its name from being an adaptor protein in the B cell receptor signaling cascade with several supporting studies showing improper development of B cells in the absence of Blnk. Blnk undergoes tyrosine phosphorylation by Syk, a B cell receptor activated kinase, which provides a platform for interaction of signaling intermediaries such as the Vav GEF and Grb2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: B cell adaptor containing SH2 domain; B cell linker protein; B-cell activation; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; B-cell linker protein; Cytoplasmic adapter protein; Lymphocyte antigen 57; MGC111051; SLP-65; Src homology 2 domain-containing leukocyte protein of 65 kDa; Src homology [SH2] domain-containing leukocyte protein of 65 kD
Gene Aliases: AGM4; BASH; Bca; BLNK; BLNK-S; Ly-57; LY57; Lyw-57; SLP-65; SLP65
UniProt ID: (Human) Q8WV28, (Mouse) Q9QUN3
Entrez Gene ID: (Human) 29760, (Mouse) 17060
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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