Proteintech

BLOC1S1 Polyclonal Antibody

BLOC1S1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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BLOC1S1 Antibody (19687-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human small intestine slide using 19687-1-AP ( BLOC1S1-Specific Antibody) at dilution of 1:50.

BLOC1S1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

19687-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 7 publications 7 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.17 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

The antibody is specific to NLOC1S1.

Target Information

BLOC1S1 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules (Starcevic and Dell'Angelica, 2004 ).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

NAD⁺ Repletion Reverses Heart Failure With Preserved Ejection Fraction.

Circulation research

Tong D,Schiattarella GG,Jiang N,Altamirano F,Szweda PA,Elnwasany A,Lee DI,Yoo H,Kass DA,Szweda LI,Lavandero S,Verdin E,Gillette TG,Hill JA

Fri May 28 00:00:00 UTC 2021

Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α.

Nature communications

Le Thomas A,Ferri E,Marsters S,Harnoss JM,Lawrence DA,Zuazo-Gaztelu I,Modrusan Z,Chan S,Solon M,Chalouni C,Li W,Koeppen H,Rudolph J,Wang W,Wu TD,Walter P,Ashkenazi A

Wed Dec 15 00:00:00 UTC 2021

General Control of Amino Acid Synthesis 5-Like 1-Mediated Acetylation of Manganese Superoxide Dismutase Regulates Oxidative Stress in Diabetic Kidney Disease.

Oxidative medicine and cellular longevity

Lv T,Lu Y,Liu Y,Feng H,Li C,Sheng W,Cui Z,Zhu S,Gu X,Yang Z,Wan Q

Thu May 20 00:00:00 UTC 2021

HIV-1 Vpr protein impairs lysosome clearance causing SNCA/alpha-synuclein accumulation in neurons.

Autophagy

Santerre M,Arjona SP,Allen CN,Callen S,Buch S,Sawaya BE

Thu Jul 01 00:00:00 UTC 2021

A guide to assessing endoplasmic reticulum homeostasis and stress in mammalian systems.

The FEBS journal

Sicari D,Delaunay-Moisan A,Combettes L,Chevet E,Igbaria A

Wed Jan 01 00:00:00 UTC 2020

A guide to assessing endoplasmic reticulum homeostasis and stress in mammalian systems.

The FEBS journal

Sicari D,Delaunay-Moisan A,Combettes L,Chevet E,Igbaria A

Wed Jan 01 00:00:00 UTC 2020

A guide to assessing endoplasmic reticulum homeostasis and stress in mammalian systems.

The FEBS journal

Sicari D,Delaunay-Moisan A,Combettes L,Chevet E,Igbaria A

Wed Jan 01 00:00:00 UTC 2020

A guide to assessing endoplasmic reticulum homeostasis and stress in mammalian systems.

The FEBS journal

Sicari D,Delaunay-Moisan A,Combettes L,Chevet E,Igbaria A

Wed Jan 01 00:00:00 UTC 2020

GCN5L1 controls renal lipotoxicity through regulating acetylation of fatty acid oxidation enzymes.

Journal of physiology and biochemistry

Lv T,Hu Y,Ma Y,Zhen J,Xin W,Wan Q

Fri Nov 01 00:00:00 UTC 2019

GCN5L1 controls renal lipotoxicity through regulating acetylation of fatty acid oxidation enzymes.

Journal of physiology and biochemistry

Lv T,Hu Y,Ma Y,Zhen J,Xin W,Wan Q

Fri Nov 01 00:00:00 UTC 2019

GCN5L1 controls renal lipotoxicity through regulating acetylation of fatty acid oxidation enzymes.

Journal of physiology and biochemistry

Lv T,Hu Y,Ma Y,Zhen J,Xin W,Wan Q

Fri Nov 01 00:00:00 UTC 2019

GCN5L1 controls renal lipotoxicity through regulating acetylation of fatty acid oxidation enzymes.

Journal of physiology and biochemistry

Lv T,Hu Y,Ma Y,Zhen J,Xin W,Wan Q

Fri Nov 01 00:00:00 UTC 2019

Snapin promotes HIV-1 transmission from dendritic cells by dampening TLR8 signaling.

The EMBO journal

Khatamzas E,Hipp MM,Gaughan D,Pichulik T,Leslie A,Fernandes RA,Muraro D,Booth S,Zausmer K,Sun MY,Kessler B,Rowland-Jones S,Cerundolo V,Simmons A

Mon Oct 16 00:00:00 UTC 2017

Snapin promotes HIV-1 transmission from dendritic cells by dampening TLR8 signaling.

The EMBO journal

Khatamzas E,Hipp MM,Gaughan D,Pichulik T,Leslie A,Fernandes RA,Muraro D,Booth S,Zausmer K,Sun MY,Kessler B,Rowland-Jones S,Cerundolo V,Simmons A

Mon Oct 16 00:00:00 UTC 2017

Bioinformatics

Protein Aliases: biogenesis of lysosomal organelles complex-1, subunit 1; Biogenesis of lysosome-related organelles complex 1 subunit 1; biogenesis of lysosome-related organelles complex-1, subunit 1; BLOC subunit 1; BLOC-1 subunit 1; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 1; GCN5 general control of amino acid synthesis-like 1; GCN5 general control of amino-acid synthesis 5-like 1; GCN5-like protein 1; general control of amino acid synthesis, yeast homolog-like 1; general control of amino acid synthesis-like 1; MTA1-interacting coactivator; Protein acetyltransferase BLOC1S1; Protein RT14

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Gene Aliases: AI839753; BLOC1S1; BLOS1; BORCS1; GCN5L1; MICoA; RT14

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UniProt ID: (Human) P78537, (Mouse) O55102, (Rat) D3ZKU7

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Entrez Gene ID: (Human) 2647, (Mouse) 14533, (Rat) 288785

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Function(s)

protein binding molecular_function

Process(es)

anterograde axonal transport aerobic respiration endosomal transport peptidyl-lysine acetylation neuron projection development lysosome localization melanosome organization anterograde synaptic vesicle transport platelet dense granule organization mitophagy in response to mitochondrial depolarization biological_process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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BLOC1S1 Polyclonal Antibody

BLOC1S1 Antibody (19687-1-AP) in IHC (P)

Product Details

19687-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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