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Invitrogen
BLOC1S2 Polyclonal Antibody
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BLOC1S2 Antibody (PA5-25452) in IHC (P)
Immunohistochemistry analysis of BLOC1S2 in formalin fixed and paraffin embedded human cervix carcinoma. Samples were incubated with BLOC1S2 polyclonal antibody (Product # PA5-25452) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-25452
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 14-40 amino acids from the central region of human BLOC1S2
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2542952
Product Specific Information
This antibody is predicted to react with non-human primate based on sequence homology.
Target Information
BLOC1S2 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 11 kDa centrosome associated protein; biogenesis of lysosomal organelles complex-1, subunit 2; Biogenesis of lysosome-related organelles complex 1 subunit 2; biogenesis of lysosome-related organelles complex-1, subunit 2; biogenesis of lysosome-related organelles complex-1, subunit 2A; BLOC-1 subunit 2; centrosomal 10 kDa protein; centrosome protein oncogene; Centrosome-associated protein; RP11-316M21.4
Gene Aliases: 2410089B13Rik; BLOC1S2; Bloc1s2a; BLOS2; BORCS2; CEAP; CEAP11
UniProt ID: (Human) Q6QNY1, (Mouse) Q9CWG9
Entrez Gene ID: (Human) 282991, (Mouse) 73689
anterograde axonal transport
positive regulation of cell proliferation
extrinsic apoptotic signaling pathway via death domain receptors
neuron projection development
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
anterograde synaptic vesicle transport
mitochondrial outer membrane permeabilization
lysosome localization
melanosome organization
platelet dense granule organization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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