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Invitrogen
BMP-8A Polyclonal Antibody
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Product Details
PA5-28849
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human BMP8A. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.38 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2546325
Product Specific Information
Recommended positive controls: 293T, A431, H1299, HeLaS3, Raji.
Predicted reactivity: Mouse (100%), Rat (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Bone morphogenic proteins (BMPs) are members of the TGF beta superfamily. BMPs are involved in the induction of cartilage and bone formation.BMP-8 is thought to be involved in early development, as detectable expression has not been found in adult organs. Two BMP-8 proteins exist, namely BMP-8A and BMP-8B (also designated OP-2), and are encoded by two distinct genes.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BMP; BMP-8A; BMP-8B; BMP8B; Bone morphogenetic protein; Bone morphogenetic protein 8A; OP-2; Osteogenic protein 2
Gene Aliases: Bmp-8; Bmp7r1; Bmp8; BMP8A; OP-2; OP2
UniProt ID: (Human) Q7Z5Y6, (Mouse) P34821
Entrez Gene ID: (Human) 353500, (Mouse) 12163
ossification
osteoblast differentiation
diet induced thermogenesis
transforming growth factor beta receptor signaling pathway
multicellular organism development
germ cell development
spermatogenesis
positive regulation of pathway-restricted SMAD protein phosphorylation
cell differentiation
BMP signaling pathway
growth
regulation of apoptotic process
regulation of MAPK cascade
negative regulation of insulin secretion
cartilage development
SMAD protein signal transduction
regulation of energy homeostasis
cell development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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