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Product Details
11074-2-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BORIS Fusion Protein Ag1547 (361-663 aa encoded by BC130486)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Polyclonal anti-CFCFL antibody (11074-2-AP) is produced by immunizing animals with part of C-terminal chain of CTCFL and detects a 75 kDa and a 55 kDa band.
Immunogen sequence: VRSHTGERP FQCCQCSYAS RDTYKLKRHM RTHSGEKPYE CHICHTRFTQ SGTMKIHILQ KHGENVPKYQ CPHCATIIAR KSDLRVHMRN LHAYSAAELK CRYCSAVFHE RYALIQHQKT HKNEKRFKCK HCSYACKQER HMTAHIRTHT GEKPFTCLSC NKCFRQKQLL NAHFRKYHDA NFIPTVYKCS KCGKGFSRWI NLHRHSEKCG SGEAKSAASG KGRRTRKRKQ TILKEATKGQ KEAAKGWKEA ANGDEAAAEE ASTTKGEQFP GEMFPVACRE TTARVKEEVD EGVTCEMLLN TMDK (361-663 aa encoded by B C130486)
Target Information
CTCFL is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes. CTCFL is normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BORIS; BORIS like protein; BORIS-like protein; Brother of the regulator of imprinted sites; Cancer/testis antigen 27; CCCTC-binding factor; CCCTC-binding factor (zinc finger protein)-like; CT27; CTCF paralog; CTCF T; CTCF-like protein; HMG 1L1; HMG-1L1; likely orthologue of H. sapiens CCCTC-binding factor-like protein (CTCFL); MGC163358; MGC169105; MGC169106; putative high mobility group protein 1-like 1; putative high mobility group protein B1-like 1; Transcriptional repressor CTCFL; Zinc finger protein CTCF-T
Gene Aliases: BORIS; CT27; CTCF-T; CTCFL; dJ579F20.2; HMGB1L1; OTTMUSG00000016680
UniProt ID: (Human) Q8NI51, (Mouse) A2APF3
Entrez Gene ID: (Human) 140690, (Mouse) 664799
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
protein binding
histone binding
sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding
nucleic acid binding
regulation of gene expression by genetic imprinting
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
positive regulation of gene expression
chromatin modification
histone methylation
DNA methylation involved in gamete generation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of histone H3-K4 methylation
cell cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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