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Bethyl Laboratories
BRD2 Recombinant Rabbit Monoclonal Antibody (BL-167-2A2)
FIGURE: 1 / 3
BRD2 Antibody (A700-008) in WB
Detection of human BRD2 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, MCF-7, Hep-G2, A-549, SW620, SK-MEL-28, and Jurkat cells prepared using NETN lysis buffer. Antibody: Rabbit anti-BRD2 recombinant monoclonal antibody [BL-167-2A2] (Product # A700-008 lot 3) used at 1:1,000. Secondary: HRP-conjugated goat anti-rabbit IgG (A120-101P). Detection: Chemiluminescence with an exposure time of 10 seconds.
Product Details
A700-008
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
BL-167-2A2
Immunogen
Synthetic peptide representing a region between residues 675 and 725 of human bromodomain containing 2.
Conjugate
Form
Liquid
Concentration
40 µg/mL
Purification
Ion-exchange chromatography
Storage buffer
BBS, pH 8.2, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatibility complex (MHC) class II region on chromosome 6p21. 3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene, but the full-length nature of some of these variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bromodomain-containing protein 2; DADB-17J1.3; DKFZp686N0336; female sterile homeotic-related gene 1; Female sterile homeotic-related protein 1; FLJ31942; Fsrg-1; O27.1.1; really interesting new gene 3 protein; RING3 protein
Gene Aliases: AW228947; BRD2; D17H6S113E; D6S113E; Frg-1; FSH; Fsrg-1; FSRG1; Kiaa4005; KIAA9001; mKIAA4005; NAT; O27.1.1; RING3; RNF3
UniProt ID: (Human) P25440, (Mouse) Q7JJ13
Entrez Gene ID: (Human) 6046, (Mouse) 14312
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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