Proteintech

BRD7 Polyclonal Antibody

BRD7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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BRD7 Antibody (51009-2-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using (Product # 51009-2-AP) (BRD7 antibody) at dilution of 1:100 (under 10x lens).

Product Image Gallery

Product Details

51009-2-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2400

View 22 publications 22 publications

Immunohistochemistry (IHC)

View 9 publications 9 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 6 publications 6 publications

Immunoprecipitation (IP)

Assay-dependent

View 3 publications 3 publications

ChIP assay (ChIP)

Assay-dependent

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

BRD7 Fusion Protein Ag3911 (1-350 aa encoded by BC050728)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MGKKHKKHK SDKHLYEEYV EKPLKLVLKV GGNEVTELST GSSGHDSSLF EDKNDHDKHK DRKRKKRKKG EKQIPGEEKG RKRRRVKEDK KKRDRDRVEN EAEKDLQCHA PVRLDLPPEK PLTSSLAKQE EVEQTPLQEA LNQLMRQLQR KDPSAFFSFP VTDFIAPGYS MIIKHPMDFS TMKEKIKNND YQSIEELKDN FKLMCTNAMI YNKPETIYYK AAKKLLHSGM KILSQERIQS LKQSIDFMAD LQKTRKQKDG TDTSQSGEDG GCWQREREDS GDAEAHAFKS PSKENKKKDK DMLEDKFKSN NLEREQEQLD RIVKESGGKL TRRLVNSQCE FERRKPDGTT T (1-350 aa encoded by BC050728)

Target Information

BRD7 acts both as coactivator and as corepressor. For example, it activates the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. In addition, it is required for TP53-mediated cell-cycle arrest in response to oncogene activation. BRD7 promotes acetylation of TP53 at Lys-382, and thereby promotes efficient recruitment of TP53 to target promoters, inhibiting cell cycle progression from G1 to S phase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

BRD7 inhibits enhancer activity and expression of BIRC2 to suppress tumor growth and metastasis in nasopharyngeal carcinoma.

Cell death & disease

Li M,Wei Y,Liu Y,Wei J,Zhou X,Duan Y,Chen S,Xue C,Zhan Y,Zheng L,Deng H,Tang F,Fan S,Xiong W,Li G,Tan M,Zhou M

Tue Feb 14 00:00:00 UTC 2023

FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression.

Cell reports

Zhang Y,He B,Zhang D,Zhang Y,Chen C,Zhang W,Yang S,Yao M,Cui G,Gu J,Wang T,Lin Z,Fan Y,Xiong Z,Hao Y

Tue Mar 28 00:00:00 UTC 2023

Upregulation of BRD7 protects podocytes against high glucose-induced apoptosis by enhancing Nrf2 in a GSK-3β-dependent manner.

Tissue & cell

Yu X,Jiang N,Li J,Li X,He S

Wed Jun 01 00:00:00 UTC 2022

Upregulation of BRD7 protects podocytes against high glucose-induced apoptosis by enhancing Nrf2 in a GSK-3β-dependent manner.

Tissue & cell

Yu X,Jiang N,Li J,Li X,He S

Wed Jun 01 00:00:00 UTC 2022

BRD7 restrains TNF-α-induced proliferation and migration of airway smooth muscle cells by inhibiting notch signaling.

Experimental lung research

Li H,Yang T,Chen T,Liu Y,Pang Y,Yang L

Tue Sep 13 00:00:00 UTC 2022

BRD7 restrains TNF-α-induced proliferation and migration of airway smooth muscle cells by inhibiting notch signaling.

Experimental lung research

Li H,Yang T,Chen T,Liu Y,Pang Y,Yang L

Tue Sep 13 00:00:00 UTC 2022

Transforming Stimulated Clone 22 (TSC-22) Interacts Directly with Bromodomain-Containing Protein 7 (BRD7) to Enhance the Inhibition of Extracellular Signal-Regulate Kinase (ERK) Pathway in Ovarian Cancer.

Development & reproduction

Lee SH,Choi D

Thu Sep 01 00:00:00 UTC 2022

Development & reproduction

Lee SH,Choi D

Thu Sep 01 00:00:00 UTC 2022

Development & reproduction

Lee SH,Choi D

Thu Sep 01 00:00:00 UTC 2022

BRD7 Stabilizes P53 via Dephosphorylation of MDM2 to Inhibit Tumor Growth in Breast Cancer Harboring Wild-type P53.

Journal of Cancer

Luo Y,Wang X,Niu W,Zhou Y,Li M,Ma J,Yang J,Fan S,Zeng Z,Xiong W,Li X,Li G,Xiao J,Zhou M

Tue Apr 05 00:00:00 UTC 2022

BRD7 Stabilizes P53 via Dephosphorylation of MDM2 to Inhibit Tumor Growth in Breast Cancer Harboring Wild-type P53.

Journal of Cancer

Luo Y,Wang X,Niu W,Zhou Y,Li M,Ma J,Yang J,Fan S,Zeng Z,Xiong W,Li X,Li G,Xiao J,Zhou M

Tue Apr 05 00:00:00 UTC 2022

BRD7 Stabilizes P53 via Dephosphorylation of MDM2 to Inhibit Tumor Growth in Breast Cancer Harboring Wild-type P53.

Journal of Cancer

Luo Y,Wang X,Niu W,Zhou Y,Li M,Ma J,Yang J,Fan S,Zeng Z,Xiong W,Li X,Li G,Xiao J,Zhou M

Tue Apr 05 00:00:00 UTC 2022

BRD7 Stabilizes P53 via Dephosphorylation of MDM2 to Inhibit Tumor Growth in Breast Cancer Harboring Wild-type P53.

Journal of Cancer

Luo Y,Wang X,Niu W,Zhou Y,Li M,Ma J,Yang J,Fan S,Zeng Z,Xiong W,Li X,Li G,Xiao J,Zhou M

Tue Apr 05 00:00:00 UTC 2022

SS18 regulates pluripotent-somatic transition through phase separation.

Nature communications

Kuang J,Zhai Z,Li P,Shi R,Guo W,Yao Y,Guo J,Zhao G,He J,Xu S,Wu C,Yu S,Zhou C,Wu L,Qin Y,Cai B,Li W,Wu Z,Li X,Chu S,Yang T,Wang B,Cao S,Li D,Zhang X,Chen J,Liu J,Pei D

Fri Jul 02 00:00:00 UTC 2021

BRD7 Promotes Cell Proliferation and Tumor Growth Through Stabilization of c-Myc in Colorectal Cancer.

Frontiers in cell and developmental biology

Zhao R,Liu Y,Wu C,Li M,Wei Y,Niu W,Yang J,Fan S,Xie Y,Li H,Wang W,Zeng Z,Xiong W,Li X,Li G,Zhou M

Sat Jun 12 00:00:00 UTC 2021

BRD7 Promotes Cell Proliferation and Tumor Growth Through Stabilization of c-Myc in Colorectal Cancer.

Frontiers in cell and developmental biology

Zhao R,Liu Y,Wu C,Li M,Wei Y,Niu W,Yang J,Fan S,Xie Y,Li H,Wang W,Zeng Z,Xiong W,Li X,Li G,Zhou M

Sat Jun 12 00:00:00 UTC 2021

A Role for SMARCB1 in Synovial Sarcomagenesis Reveals That SS18-SSX Induces Canonical BAF Destruction.

Cancer discovery

Li J,Mulvihill TS,Li L,Barrott JJ,Nelson ML,Wagner L,Lock IC,Pozner A,Lambert SL,Ozenberger BB,Ward MB,Grossmann AH,Liu T,Banito A,Cairns BR,Jones KB

Fri Oct 01 00:00:00 UTC 2021

BRD7 suppresses invasion and metastasis in breast cancer by negatively regulating YB1-induced epithelial-mesenchymal transition.

Journal of experimental & clinical cancer research : CR

Niu W,Luo Y,Zhou Y,Li M,Wu C,Duan Y,Wang H,Fan S,Li Z,Xiong W,Li X,Li G,Ren C,Li H,Zhou M

Fri Feb 07 00:00:00 UTC 2020

BRD7 suppresses invasion and metastasis in breast cancer by negatively regulating YB1-induced epithelial-mesenchymal transition.

Journal of experimental & clinical cancer research : CR

Niu W,Luo Y,Zhou Y,Li M,Wu C,Duan Y,Wang H,Fan S,Li Z,Xiong W,Li X,Li G,Ren C,Li H,Zhou M

Fri Feb 07 00:00:00 UTC 2020

Clinical significance of bromodomain-containing protein 7 and its association with tumor progression in prostate cancer.

Oncology letters

Liang Y,Dong B,Shen J,Ma C,Ma Z

Tue Jan 01 00:00:00 UTC 2019

Clinical significance of bromodomain-containing protein 7 and its association with tumor progression in prostate cancer.

Oncology letters

Liang Y,Dong B,Shen J,Ma C,Ma Z

Tue Jan 01 00:00:00 UTC 2019

Bromodomain‑containing protein 7 sensitizes breast cancer cells to paclitaxel by activating Bcl2‑antagonist/killer protein.

Oncology reports

Ma J,Niu W,Wang X,Zhou Y,Wang H,Liu F,Liu Y,Guo J,Xiong W,Zeng Z,Fan S,Li X,Nie X,Li G,Gui R,Luo Y,Zhou M

Fri Mar 01 00:00:00 UTC 2019

Bromodomain‑containing protein 7 sensitizes breast cancer cells to paclitaxel by activating Bcl2‑antagonist/killer protein.

Oncology reports

Ma J,Niu W,Wang X,Zhou Y,Wang H,Liu F,Liu Y,Guo J,Xiong W,Zeng Z,Fan S,Li X,Nie X,Li G,Gui R,Luo Y,Zhou M

Fri Mar 01 00:00:00 UTC 2019

BRD7 expression and c-Myc activation forms a double-negative feedback loop that controls the cell proliferation and tumor growth of nasopharyngeal carcinoma by targeting oncogenic miR-141.

Journal of experimental & clinical cancer research : CR

Liu Y,Zhao R,Wei Y,Li M,Wang H,Niu W,Zhou Y,Qiu Y,Fan S,Zhan Y,Xiong W,Zhou Y,Li X,Li Z,Li G,Zhou M

Tue Mar 20 00:00:00 UTC 2018

BRD7 expression and c-Myc activation forms a double-negative feedback loop that controls the cell proliferation and tumor growth of nasopharyngeal carcinoma by targeting oncogenic miR-141.

Journal of experimental & clinical cancer research : CR

Liu Y,Zhao R,Wei Y,Li M,Wang H,Niu W,Zhou Y,Qiu Y,Fan S,Zhan Y,Xiong W,Zhou Y,Li X,Li Z,Li G,Zhou M

Tue Mar 20 00:00:00 UTC 2018

BRD7 expression and c-Myc activation forms a double-negative feedback loop that controls the cell proliferation and tumor growth of nasopharyngeal carcinoma by targeting oncogenic miR-141.

Journal of experimental & clinical cancer research : CR

Liu Y,Zhao R,Wei Y,Li M,Wang H,Niu W,Zhou Y,Qiu Y,Fan S,Zhan Y,Xiong W,Zhou Y,Li X,Li Z,Li G,Zhou M

Tue Mar 20 00:00:00 UTC 2018

BRD7 expression and c-Myc activation forms a double-negative feedback loop that controls the cell proliferation and tumor growth of nasopharyngeal carcinoma by targeting oncogenic miR-141.

Journal of experimental & clinical cancer research : CR

Liu Y,Zhao R,Wei Y,Li M,Wang H,Niu W,Zhou Y,Qiu Y,Fan S,Zhan Y,Xiong W,Zhou Y,Li X,Li Z,Li G,Zhou M

Tue Mar 20 00:00:00 UTC 2018

BRD7 inhibits the Warburg effect and tumor progression through inactivation of HIF1α/LDHA axis in breast cancer.

Cell death & disease

Niu W,Luo Y,Wang X,Zhou Y,Li H,Wang H,Fu Y,Liu S,Yin S,Li J,Zhao R,Liu Y,Fan S,Li Z,Xiong W,Li X,Li G,Ren C,Tan M,Zhou M

Tue May 01 00:00:00 UTC 2018

BRD7 inhibits the Warburg effect and tumor progression through inactivation of HIF1α/LDHA axis in breast cancer.

Cell death & disease

Niu W,Luo Y,Wang X,Zhou Y,Li H,Wang H,Fu Y,Liu S,Yin S,Li J,Zhao R,Liu Y,Fan S,Li Z,Xiong W,Li X,Li G,Ren C,Tan M,Zhou M

Tue May 01 00:00:00 UTC 2018

BRD7 inhibits the Warburg effect and tumor progression through inactivation of HIF1α/LDHA axis in breast cancer.

Cell death & disease

Niu W,Luo Y,Wang X,Zhou Y,Li H,Wang H,Fu Y,Liu S,Yin S,Li J,Zhao R,Liu Y,Fan S,Li Z,Xiong W,Li X,Li G,Ren C,Tan M,Zhou M

Tue May 01 00:00:00 UTC 2018

BRD7 inhibits the Warburg effect and tumor progression through inactivation of HIF1α/LDHA axis in breast cancer.

Cell death & disease

Niu W,Luo Y,Wang X,Zhou Y,Li H,Wang H,Fu Y,Liu S,Yin S,Li J,Zhao R,Liu Y,Fan S,Li Z,Xiong W,Li X,Li G,Ren C,Tan M,Zhou M

Tue May 01 00:00:00 UTC 2018

BRD7 inhibits the Warburg effect and tumor progression through inactivation of HIF1α/LDHA axis in breast cancer.

Cell death & disease

Niu W,Luo Y,Wang X,Zhou Y,Li H,Wang H,Fu Y,Liu S,Yin S,Li J,Zhao R,Liu Y,Fan S,Li Z,Xiong W,Li X,Li G,Ren C,Tan M,Zhou M

Tue May 01 00:00:00 UTC 2018

BRD7 plays an anti-inflammatory role during early acute inflammation by inhibiting activation of the NF-кB signaling pathway.

Cellular & molecular immunology

Zhao R,Liu Y,Wang H,Yang J,Niu W,Fan S,Xiong W,Ma J,Li X,Phillips JB,Tan M,Qiu Y,Li G,Zhou M

Sun Oct 01 00:00:00 UTC 2017

Bromodomain containing protein represses the Ras/Raf/MEK/ERK pathway to attenuate human hepatoma cell proliferation during HCV infection.

Cancer letters

Zhang Q,Wei L,Yang H,Yang W,Yang Q,Zhang Z,Wu K,Wu J

Mon Feb 01 00:00:00 UTC 2016

Bromodomain containing protein represses the Ras/Raf/MEK/ERK pathway to attenuate human hepatoma cell proliferation during HCV infection.

Cancer letters

Zhang Q,Wei L,Yang H,Yang W,Yang Q,Zhang Z,Wu K,Wu J

Mon Feb 01 00:00:00 UTC 2016

miR-141 is involved in BRD7-mediated cell proliferation and tumor formation through suppression of the PTEN/AKT pathway in nasopharyngeal carcinoma.

Cell death & disease

Liu Y,Zhao R,Wang H,Luo Y,Wang X,Niu W,Zhou Y,Wen Q,Fan S,Li X,Xiong W,Ma J,Li X,Tan M,Li G,Zhou M

Thu Mar 24 00:00:00 UTC 2016

miR-141 is involved in BRD7-mediated cell proliferation and tumor formation through suppression of the PTEN/AKT pathway in nasopharyngeal carcinoma.

Cell death & disease

Liu Y,Zhao R,Wang H,Luo Y,Wang X,Niu W,Zhou Y,Wen Q,Fan S,Li X,Xiong W,Ma J,Li X,Tan M,Li G,Zhou M

Thu Mar 24 00:00:00 UTC 2016

miR-141 is involved in BRD7-mediated cell proliferation and tumor formation through suppression of the PTEN/AKT pathway in nasopharyngeal carcinoma.

Cell death & disease

Liu Y,Zhao R,Wang H,Luo Y,Wang X,Niu W,Zhou Y,Wen Q,Fan S,Li X,Xiong W,Ma J,Li X,Tan M,Li G,Zhou M

Thu Mar 24 00:00:00 UTC 2016

miR-141 is involved in BRD7-mediated cell proliferation and tumor formation through suppression of the PTEN/AKT pathway in nasopharyngeal carcinoma.

Cell death & disease

Liu Y,Zhao R,Wang H,Luo Y,Wang X,Niu W,Zhou Y,Wen Q,Fan S,Li X,Xiong W,Ma J,Li X,Tan M,Li G,Zhou M

Thu Mar 24 00:00:00 UTC 2016

Knockout of BRD7 results in impaired spermatogenesis and male infertility.

Scientific reports

Wang H,Zhao R,Guo C,Jiang S,Yang J,Xu Y,Liu Y,Fan L,Xiong W,Ma J,Peng S,Zeng Z,Zhou Y,Li X,Li Z,Li X,Schmitt DC,Tan M,Li G,Zhou M

Tue Feb 16 00:00:00 UTC 2016

Knockout of BRD7 results in impaired spermatogenesis and male infertility.

Scientific reports

Wang H,Zhao R,Guo C,Jiang S,Yang J,Xu Y,Liu Y,Fan L,Xiong W,Ma J,Peng S,Zeng Z,Zhou Y,Li X,Li Z,Li X,Schmitt DC,Tan M,Li G,Zhou M

Tue Feb 16 00:00:00 UTC 2016

Knockout of BRD7 results in impaired spermatogenesis and male infertility.

Scientific reports

Wang H,Zhao R,Guo C,Jiang S,Yang J,Xu Y,Liu Y,Fan L,Xiong W,Ma J,Peng S,Zeng Z,Zhou Y,Li X,Li Z,Li X,Schmitt DC,Tan M,Li G,Zhou M

Tue Feb 16 00:00:00 UTC 2016

Knockout of BRD7 results in impaired spermatogenesis and male infertility.

Scientific reports

Wang H,Zhao R,Guo C,Jiang S,Yang J,Xu Y,Liu Y,Fan L,Xiong W,Ma J,Peng S,Zeng Z,Zhou Y,Li X,Li Z,Li X,Schmitt DC,Tan M,Li G,Zhou M

Tue Feb 16 00:00:00 UTC 2016

Bromodomain-containing protein 7 (BRD7) as a potential tumor suppressor in hepatocellular carcinoma.

Oncotarget

Chen CL,Wang Y,Pan QZ,Tang Y,Wang QJ,Pan K,Huang LX,He J,Zhao JJ,Jiang SS,Zhang XF,Zhang HX,Zhou ZQ,Weng de S,Xia JC

Tue Mar 29 00:00:00 UTC 2016

Bromodomain-containing protein 7 (BRD7) as a potential tumor suppressor in hepatocellular carcinoma.

Oncotarget

Chen CL,Wang Y,Pan QZ,Tang Y,Wang QJ,Pan K,Huang LX,He J,Zhao JJ,Jiang SS,Zhang XF,Zhang HX,Zhou ZQ,Weng de S,Xia JC

Tue Mar 29 00:00:00 UTC 2016

Bromodomain-containing protein 7 (BRD7) as a potential tumor suppressor in hepatocellular carcinoma.

Oncotarget

Chen CL,Wang Y,Pan QZ,Tang Y,Wang QJ,Pan K,Huang LX,He J,Zhao JJ,Jiang SS,Zhang XF,Zhang HX,Zhou ZQ,Weng de S,Xia JC

Tue Mar 29 00:00:00 UTC 2016

Bromodomain-containing protein 7 (BRD7) as a potential tumor suppressor in hepatocellular carcinoma.

Oncotarget

Chen CL,Wang Y,Pan QZ,Tang Y,Wang QJ,Pan K,Huang LX,He J,Zhao JJ,Jiang SS,Zhang XF,Zhang HX,Zhou ZQ,Weng de S,Xia JC

Tue Mar 29 00:00:00 UTC 2016

Inactivation of BRD7 results in impaired cognitive behavior and reduced synaptic plasticity of the medial prefrontal cortex.

Behavioural brain research

Xu Y,Cao W,Zhou M,Li C,Luo Y,Wang H,Zhao R,Jiang S,Yang J,Liu Y,Wang X,Li X,Xiong W,Ma J,Peng S,Zeng Z,Li X,Tan M,Li G

Mon Jun 01 00:00:00 UTC 2015

Inactivation of BRD7 results in impaired cognitive behavior and reduced synaptic plasticity of the medial prefrontal cortex.

Behavioural brain research

Xu Y,Cao W,Zhou M,Li C,Luo Y,Wang H,Zhao R,Jiang S,Yang J,Liu Y,Wang X,Li X,Xiong W,Ma J,Peng S,Zeng Z,Li X,Tan M,Li G

Mon Jun 01 00:00:00 UTC 2015

Inactivation of BRD7 results in impaired cognitive behavior and reduced synaptic plasticity of the medial prefrontal cortex.

Behavioural brain research

Xu Y,Cao W,Zhou M,Li C,Luo Y,Wang H,Zhao R,Jiang S,Yang J,Liu Y,Wang X,Li X,Xiong W,Ma J,Peng S,Zeng Z,Li X,Tan M,Li G

Mon Jun 01 00:00:00 UTC 2015

Inactivation of BRD7 results in impaired cognitive behavior and reduced synaptic plasticity of the medial prefrontal cortex.

Behavioural brain research

Xu Y,Cao W,Zhou M,Li C,Luo Y,Wang H,Zhao R,Jiang S,Yang J,Liu Y,Wang X,Li X,Xiong W,Ma J,Peng S,Zeng Z,Li X,Tan M,Li G

Mon Jun 01 00:00:00 UTC 2015

Inactivation of BRD7 results in impaired cognitive behavior and reduced synaptic plasticity of the medial prefrontal cortex.

Behavioural brain research

Xu Y,Cao W,Zhou M,Li C,Luo Y,Wang H,Zhao R,Jiang S,Yang J,Liu Y,Wang X,Li X,Xiong W,Ma J,Peng S,Zeng Z,Li X,Tan M,Li G

Mon Jun 01 00:00:00 UTC 2015

BRD7, a subunit of SWI/SNF complexes, binds directly to BRCA1 and regulates BRCA1-dependent transcription.

Cancer research

Harte MT,O'Brien GJ,Ryan NM,Gorski JJ,Savage KI,Crawford NT,Mullan PB,Harkin DP

Mon Mar 15 00:00:00 UTC 2010

BRD7, a subunit of SWI/SNF complexes, binds directly to BRCA1 and regulates BRCA1-dependent transcription.

Cancer research

Harte MT,O'Brien GJ,Ryan NM,Gorski JJ,Savage KI,Crawford NT,Mullan PB,Harkin DP

Mon Mar 15 00:00:00 UTC 2010

BRD7, a subunit of SWI/SNF complexes, binds directly to BRCA1 and regulates BRCA1-dependent transcription.

Cancer research

Harte MT,O'Brien GJ,Ryan NM,Gorski JJ,Savage KI,Crawford NT,Mullan PB,Harkin DP

Mon Mar 15 00:00:00 UTC 2010

BRD7, a subunit of SWI/SNF complexes, binds directly to BRCA1 and regulates BRCA1-dependent transcription.

Cancer research

Harte MT,O'Brien GJ,Ryan NM,Gorski JJ,Savage KI,Crawford NT,Mullan PB,Harkin DP

Mon Mar 15 00:00:00 UTC 2010

Preparation of polyclonal antibody specific for BRD7 and detection of its expression pattern in the human fetus.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

Liu H,Li X,Niu Z,Zhang L,Zhou M,Huang H,He J,Zhang W,Xiao L,Tang Y,Wang L,Li G

Sun Jun 01 00:00:00 UTC 2008

Preparation of polyclonal antibody specific for BRD7 and detection of its expression pattern in the human fetus.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society

Liu H,Li X,Niu Z,Zhang L,Zhou M,Huang H,He J,Zhang W,Xiao L,Tang Y,Wang L,Li G

Sun Jun 01 00:00:00 UTC 2008

BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells.

The Journal of biological chemistry

Kaeser MD,Aslanian A,Dong MQ,Yates JR,Emerson BM

Fri Nov 21 00:00:00 UTC 2008

BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells.

The Journal of biological chemistry

Kaeser MD,Aslanian A,Dong MQ,Yates JR,Emerson BM

Fri Nov 21 00:00:00 UTC 2008

BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells.

The Journal of biological chemistry

Kaeser MD,Aslanian A,Dong MQ,Yates JR,Emerson BM

Fri Nov 21 00:00:00 UTC 2008

BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells.

The Journal of biological chemistry

Kaeser MD,Aslanian A,Dong MQ,Yates JR,Emerson BM

Fri Nov 21 00:00:00 UTC 2008

Bioinformatics

Protein Aliases: 75 kDa bromodomain protein; bromodomain protein 75 kDa; bromodomain-containing 7; Bromodomain-containing protein 7; Protein CELTIX-1; protein tyrosine phosphatase, non-receptor type 13 interacting protein

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Gene Aliases: BP75; BRD7; CELTIX1; NAG4; Ptpn13ip

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UniProt ID: (Human) Q9NPI1, (Mouse) O88665

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Entrez Gene ID: (Human) 29117, (Mouse) 26992, (Rat) 361374

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Function(s)

p53 binding transcription coactivator activity transcription corepressor activity protein binding transcription factor binding histone binding transcription regulatory region DNA binding lysine-acetylated histone binding molecular_function

Process(es)

transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter cell cycle negative regulation of cell proliferation Wnt signaling pathway positive regulation of histone acetylation negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated negative regulation of nucleic acid-templated transcription negative regulation of G1/S transition of mitotic cell cycle biological_process regulation of signal transduction by p53 class mediator

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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BRD7 Polyclonal Antibody

BRD7 Antibody (51009-2-AP) in IHC (P)

Product Details

51009-2-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

ChIP assay (ChIP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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