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Immunogen sequence: TVKQERLDF EETENKGIHE LVDIREPSAE IKVEPAEPEP VISGAEIVAG VVPATSMEPP ELRSQDLDEE LGSTAAGEIV EADVAIGKGD ETPLTNVKTE ASPESMLSPS HGSNPIEDPL EAETQHKFEM SDSLKEESGT IFGSQIKDAP GEDEEEDGVS EAASLEEPKE EDQGEGYLSE MDNEPPVSES DDGFSIHNAT LQSHTLADSI PSSPASSQFS VCSEDQEAIQ AQKIWKKAIM LVWRAAANHR YANVFLQPVT DDIAPGYHSI VQRPMDLSTI KKNIENGLIR STAEFQRDIM LMFQNAVMYN SSDHDVYHMA VEMQRDVLEQ IQQFLATQLI MQTSESGISA KSLRGRDSTR KQDASEKDSV PMGSPAFLLS LFDGGTRGRR CAIEADMKMK K (521-920 aa encoded by BC008039)
Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bromodomain-containing protein 8; p120; Skeletal muscle abundant protein; Skeletal muscle abundant protein 2; Thyroid hormone receptor coactivating protein of 120 kDa; TrCP120
Gene Aliases: 2610007E11Rik; 4432404P07Rik; BRD8; p120; SMAP; SMAP2
UniProt ID: (Human) Q9H0E9, (Mouse) Q8R3B7
Entrez Gene ID: (Human) 10902, (Mouse) 78656, (Rat) 291691
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