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Invitrogen
BRP44L Polyclonal Antibody
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FIGURE: 1 / 2
BRP44L Antibody (PA5-116938) in WB
Western blot analysis of BRP44L in extracts of various cell lines. Samples were incubated with BRP44L Polyclonal antibody (Product # PA5-116938) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-116938
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 50-109 of human MPC1 (NP_0571821)
Conjugate
Form
Liquid
Concentration
0.57 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2901568
Product Specific Information
Positive Samples: HepG2, K-562, Mouse liver, Rat heart
Immunogen sequence: IISGRMTFAL CCYSLTFMRF AYKVQPRNWL LFACHATNEV AQLIQGGRLI KHEMTKTASA
Target Information
BRP44L (brain protein 44-like protein), also known as HSPC040 or CGI-129, is a 109 amino acid mitochondrial protein belonging to the UPF0041 family. The gene that encodes BRP44L maps to human chromosome 6. Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apoptosis-regulating basic protein; Brain protein 44-like protein; HSPC040 protein; Mitochondrial pyruvate carrier 1
Gene Aliases: 0610006G08Rik; 3830411I18Rik; Arbp; BRP44L; CGI-129; dJ68L15.3; HSPC040; MPC1; MPYCD; PNAS-115
UniProt ID: (Human) Q9Y5U8, (Rat) P63031, (Mouse) P63030
Entrez Gene ID: (Human) 51660, (Rat) 171087, (Mouse) 55951
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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