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Invitrogen
BRUNOL4 Polyclonal Antibody
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Product Details
PA5-31849
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human BRUNOL4. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.69 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2549322
Product Specific Information
Recommended positive controls: H1299, HCT116.
Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (97%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bruno -like 4; bruno-like 4, RNA binding protein; Bruno-like protein 4; CELF-4; CUG-BP and ETR-3 like factor 4; CUG-BP- and ETR-3-like factor 4; CUGBP; CUGBP Elav-like family member 4; LYST-interacting protein LIP9; RNA-binding protein BRUNOL-4; RNA-binding protein BRUNOL4
Gene Aliases: BRUNOL4; CELF-4; CELF4
UniProt ID: (Human) Q9BZC1
Entrez Gene ID: (Human) 56853
alternative mRNA splicing, via spliceosome
regulation of alternative mRNA splicing, via spliceosome
mRNA splice site selection
germ cell development
embryo development
negative regulation of translation
negative regulation of mRNA splicing, via spliceosome
positive regulation of mRNA splicing, via spliceosome
negative regulation of excitatory postsynaptic potential
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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