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Invitrogen
BSND Polyclonal Antibody
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FIGURE: 1 / 1
BSND Antibody (PA5-96786) in WB
Western blot analysis of BSND in extracts of various cell lines. Samples were incubated with BSND Polyclonal antibody (Product # PA5-96786) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 60s.
Product Details
PA5-96786
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 54-320 of human BSND (NP_4765171)
Conjugate
Form
Liquid
Concentration
1.77 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2808588
Product Specific Information
Immunogen sequence: CQCYPKITFV PADSDFQGIL SPKAMGLLEN GLAAEMKSPS PQPPYVRLWE EAAYDQSLPD FSHIQMKVMS YSEDHRSLLA PEMGQPKLGT SDGGEGGPGD VQAWMEAAVV IHKGSDESEG ERRLTQSWPG PLACPQGPAP LASFQDDLDM DSSEGSSPNA SPHDREEACS PQQEPQGCRC PLDRFQDFAL IDAPTLEDEP QEGQQWEIAL PNNWQRYPRT KVEEKEASDT GGEEPEKEEE DLYYGLPDGA GDLLPDKELG FEPDTQG; Positive Samples: 293T, Rat liver, Rat kidney, Rat small intestine; Cellular Location: Cell membrane, Cytoplasm, Multi-pass membrane protein
Target Information
BSND encodes an essential beta subunit for CLC chloride channels. These heteromeric channels localize to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bartter syndrome, infantile, with sensorineural deafness (Barttin); Barttin; barttin CLCNK-type chloride channel accessory beta subunit; deafness, autosomal recessive 73
Gene Aliases: BART; BSND; DFNB73
UniProt ID: (Human) Q8WZ55, (Rat) Q8R2H3, (Mouse) Q8VIM4
Entrez Gene ID: (Human) 7809, (Rat) 192675, (Mouse) 140475
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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