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Fabgennix
BTB/POZ domain-containing protein 7 Polyclonal Antibody, Biotin
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Product Details
BTBD7-BIOTIN
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 1050-1150 on human BTBD7 protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BTB (POZ) domain containing 7; BTB/POZ domain-containing protein 7; Function-unkown protein 1
Gene Aliases: 5730507E09Rik; 8030448M07; BTBD7; E130118E17Rik; FUP1; KIAA1525; mKIAA1525
UniProt ID: (Human) Q9P203, (Mouse) Q8CFE5
Entrez Gene ID: (Human) 55727, (Mouse) 238386
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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