Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This target displays homology in the following species: Human: 100%; Pig: 79%
Specifically required during spermatogenesis to promote expression of piRNA precursors. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity. Acts by facilitating transcription elongation at piRNA loci during pachytene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BTB (POZ) domain containing 18; BTB/POZ domain-containing protein 18; hCG1730474
Gene Aliases: BTBD18
UniProt ID: (Human) B2RXH4
Entrez Gene ID: (Human) 643376
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