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Immunogen sequence: IQKAFAVAFG INVLAANVHH PVLGMTGSGI HTPLESFWYH DMENPKSHLI IAQVAKNPVG LIGAENATGE TDPSHSKFLK ILSGDPYCEK DAQEVHCDEA TKWNVNAPPT FHSEMMYDNF TLVPVWGKEG YLHVCSNGLC CYLLYERPTL SKELYALGVF DGLHTVHGTY YIQVCALVRC GGLGFDTCGQ EITEATGIFE FHLWGNFSTS YIFPLFLTSG MTLEVPDQLG WENDHYFLRK SRLSSGLVTA ALYGRLYERD; Positive Samples: Mouse liver, Mouse kidney; Cellular Location: extracellular space
Biotinidase functions to recycle biotin in the body by cleaving biocytin (biotin-epsilon-lysine), a normal product of carboxylase degradation, resulting in regeneration of free biotin. Biotinidase has also been shown to have biotinyl-transferase activity. Defects in the biotinidase gene cause multiple carboxylase deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Biotinase; Biotinidase; btd {ECO:0000312|EMBL:AAH90017.1}; EC 3.5.1.12
Gene Aliases: BTD
UniProt ID: (Human) P43251, (Rat) Q5FVF9, (Mouse) Q8CIF4
Entrez Gene ID: (Human) 686, (Rat) 306262, (Mouse) 26363
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