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Proteintech
BTNL2 Polyclonal Antibody
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Product Details
25110-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BTNL2 Fusion Protein Ag18803 (24-229 aa encoded by BC127642)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: KQSEKLQTE LASLKVNGPS QPILVRVGED IQLTCYLSPK ANAQSMEVRW DRSHRYPAVH VYMDGDHVAG EQMAEYRGRT VLVSDAIDEG RLTLQILSAR PSDDGQYRCL FEKDDVYQEA SLDLKVVGLG SSPLITVEGQ EDGEMQPMCS SDGWFPQPHV PWRDMEGKTI PSSSQALTQG SHGLFHVQTL LRVTNISAVD VTCSISI (24-229 aa encoded by BC127642)
Target Information
BTNL2 (butyrophilin-like protein 2), also known as BTL-II, is a 455 amino acid single-pass type II membrane protein that acts as a negative regulator of T cell proliferation. Expressed in thymus, brain, kidney, heart, liver, small intestine, testis, ovary, pancreas and leukocytes, BTNL2 exists as at least six alternatively spliced isoforms, which are encoded by a gene located on human chromosome 6. Expression of BTNL2 isoform 3 is associated with susceptibility to sarcoidosis type 2 (SS2), an immune disorder that causes chronic inflammatory granulomatous lesions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BTL-II; butyrophilin-like 2 (MHC class II associated); Butyrophilin-like protein 2; butyrophylin-like MHC class II associated
Gene Aliases: BTL-II; Btl2; BTLN2; BTN7; BTNL2; Gm315; HSBLMHC1; NG9; SS2
UniProt ID: (Human) Q9UIR0, (Mouse) O70355
Entrez Gene ID: (Human) 56244, (Mouse) 547431
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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