Product References
Tumor suppressor miR-520a inhibits cell growth by negatively regulating PI3K/AKT signaling pathway in acute myeloid leukemia.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University
Xiao J,Wan F,Tian L,Li Y
MA5-11757 was used in Western Blot to show that miR-520a actively regulated cell proliferation in acute myeloid leukemia and illustrated the mechanism by which it exerts its regulatory role, emphasizing the possibility of targeting miR-520a as an efficient therapeutic strategy against human acute myeloid leukemia.
Mon Jul 01 00:00:00 UTC 2024
CircRANBP17 modulated KDM1A to regulate neuroblastoma progression by sponging miR-27b-3p.
Open medicine (Warsaw, Poland)
Zhao L,Fan J,Zhang C,Zhang Z,Dong J
Published figure using Bcl-2 monoclonal antibody (Product # MA5-11757) in Western Blot
Wed Mar 22 00:00:00 UTC 2023
Neuroprotective properties of anti-apoptotic BCL-2 proteins in 5xFAD mouse model of Alzheimer's disease.
IBRO neuroscience reports
Chernyuk D,Callens M,Polozova M,Gordeev A,Chigriai M,Rakovskaya A,Ilina A,Pchitskaya E,Van den Haute C,Vervliet T,Bultynck G,Bezprozvanny I
MA5-11757 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to indicate that Bcl-2-based strategies hold neuroprotective potential in AD models, though the underlying mechanisms requires further investigation.
Thu Jun 01 00:00:00 UTC 2023
Neuroprotective properties of anti-apoptotic BCL-2 proteins in 5xFAD mouse model of Alzheimer's disease.
IBRO neuroscience reports
Chernyuk D,Callens M,Polozova M,Gordeev A,Chigriai M,Rakovskaya A,Ilina A,Pchitskaya E,Van den Haute C,Vervliet T,Bultynck G,Bezprozvanny I
MA5-11757 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to indicate that Bcl-2-based strategies hold neuroprotective potential in AD models, though the underlying mechanisms requires further investigation.
Thu Jun 01 00:00:00 UTC 2023
Aspirin increases the efficacy of gemcitabine in pancreatic cancer by modulating the PI3K/AKT/mTOR signaling pathway and reversing epithelial‑mesenchymal transition.
Oncology letters
Zhou H,Yun X,Shu Y,Xu K
MA5-11757 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to reveal that aspirin (ASA) increased the efficacy of gemcitabine in reducing the proliferation, migration and invasion of pancreatic cancer cells and increasing their apoptosis.
Wed Mar 01 00:00:00 UTC 2023
Aspirin increases the efficacy of gemcitabine in pancreatic cancer by modulating the PI3K/AKT/mTOR signaling pathway and reversing epithelial‑mesenchymal transition.
Oncology letters
Zhou H,Yun X,Shu Y,Xu K
MA5-11757 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to reveal that aspirin (ASA) increased the efficacy of gemcitabine in reducing the proliferation, migration and invasion of pancreatic cancer cells and increasing their apoptosis.
Wed Mar 01 00:00:00 UTC 2023
Astragalus polysaccharide ameliorates steroid-induced osteonecrosis of the femoral head by regulating miR-200b-3p-mediated Wnt/β-catenin signaling pathway via inhibiting SP1 expression : Astragalus polysaccharide regulates SONFH via SP1.
BMC musculoskeletal disorders
Zhang S,Dong K,Zeng X,Wang F,Lu M
MA5-11757 was used in Western Blotting to show that APS regulated osteocyte autophagy and apoptosis via SP1/miR-200b-3p axis and activated Wnt/β-catenin signaling, thereby alleviating SONFH, shedding new insights for therapy of SONFH.
Wed May 10 00:00:00 UTC 2023
Astragalus polysaccharide ameliorates steroid-induced osteonecrosis of the femoral head by regulating miR-200b-3p-mediated Wnt/β-catenin signaling pathway via inhibiting SP1 expression : Astragalus polysaccharide regulates SONFH via SP1.
BMC musculoskeletal disorders
Zhang S,Dong K,Zeng X,Wang F,Lu M
MA5-11757 was used in Western Blotting to show that APS regulated osteocyte autophagy and apoptosis via SP1/miR-200b-3p axis and activated Wnt/β-catenin signaling, thereby alleviating SONFH, shedding new insights for therapy of SONFH.
Wed May 10 00:00:00 UTC 2023
The neuroprotective effect of quercetin nanoparticles in the therapy of neuronal damage stimulated by acrolein.
Saudi journal of biological sciences
Sanad SM,Farouk R,Nassar SE,Alshahrani MY,Suliman M,Ezzat Ahmed A,Eid Elesawi I
MA5-11757 was used in Immunohistochemistry to comprehend the immunohistochemical devastation that might arise in the cerebellum because of acrolein treatment.
Wed Nov 01 00:00:00 UTC 2023
Anti-apoptosis and anti-inflammation activity of circ_0097010 downregulation in lipopolysaccharide-stimulated periodontal ligament cells by miR-769-5p/Krüppel like factor 6 axis.
Journal of dental sciences
Sun DD,Wu X,Lin SC,Duan SY
MA5-11757 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to identify circ_0097010 as a key regulator of LPS-induced inflammation and apoptosis in hPDLCs and highlight a novel mechanism of circ_0097010 regulation through miR-769-5p/KLF6 axis.
Sun Jan 01 00:00:00 UTC 2023
The long non-coding RNA ASMTL-AS1 promotes hepatocellular carcinoma progression by sponging miR-1343-3p that suppresses LAMC1 (laminin subunit gamma 1).
Bioengineered
Mou Y,Sun Q
Published figure using Bcl-2 monoclonal antibody (Product # MA5-11757) in Western Blot
Sat Jan 01 00:00:00 UTC 2022
Identification of a novel circ_0001946/miR-1290/SOX6 ceRNA network in esophageal squamous cell cancer.
Thoracic cancer
Wang J,Yao W,Li J,Zhang Q,Wei L
Published figure using Bcl-2 monoclonal antibody (Product # MA5-11757) in Immunohistochemistry
Sun May 01 00:00:00 UTC 2022
Identification of a novel circ_0001946/miR-1290/SOX6 ceRNA network in esophageal squamous cell cancer.
Thoracic cancer
Wang J,Yao W,Li J,Zhang Q,Wei L
Published figure using Bcl-2 monoclonal antibody (Product # MA5-11757) in Immunohistochemistry
Sun May 01 00:00:00 UTC 2022
Neural stem cell-derived exosomes suppress neuronal cell apoptosis by activating autophagy via miR-374-5p/STK-4 axis in spinal cord injury.
Journal of musculoskeletal & neuronal interactions
Zhang L,Han P
MA5-11757 was used in Western Blotting to evaluate the roles of MicroRNAs (miRNAs) enclosed in the neuron-derived exosomes in the recovery of the spinal cord injury (SCI) and the mechanism.
Thu Sep 01 00:00:00 UTC 2022
Neural stem cell-derived exosomes suppress neuronal cell apoptosis by activating autophagy via miR-374-5p/STK-4 axis in spinal cord injury.
Journal of musculoskeletal & neuronal interactions
Zhang L,Han P
MA5-11757 was used in Western Blotting to evaluate the roles of MicroRNAs (miRNAs) enclosed in the neuron-derived exosomes in the recovery of the spinal cord injury (SCI) and the mechanism.
Thu Sep 01 00:00:00 UTC 2022
lncRNA ELFN1-AS1 enhances the progression of colon cancer by targeting miR-4270 to upregulate AURKB.
Open medicine (Warsaw, Poland)
Peng S,Luo Y,Chen L,Dai K,Wang Q
MA5-11757 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to show that the ELFN1-AS1/miR-4270/AURKB axis facilitates colon cancer (CC) tumorigenesis; therefore, targeting this axis might be a promising intervention in preventing CC progression.
Sat Dec 24 00:00:00 UTC 2022
lncRNA ELFN1-AS1 enhances the progression of colon cancer by targeting miR-4270 to upregulate AURKB.
Open medicine (Warsaw, Poland)
Peng S,Luo Y,Chen L,Dai K,Wang Q
MA5-11757 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to show that the ELFN1-AS1/miR-4270/AURKB axis facilitates colon cancer (CC) tumorigenesis; therefore, targeting this axis might be a promising intervention in preventing CC progression.
Sat Dec 24 00:00:00 UTC 2022
Size-Dependent Cytoprotective Effects of Selenium Nanoparticles during Oxygen-Glucose Deprivation in Brain Cortical Cells.
International journal of molecular sciences
Varlamova EG,Gudkov SV,Plotnikov EY,Turovsky EA
MA5-11757 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to study the effects of different-sized SeNPs on brain cells during oxygen-glucose deprivation.
Tue Jul 05 00:00:00 UTC 2022
Size-Dependent Cytoprotective Effects of Selenium Nanoparticles during Oxygen-Glucose Deprivation in Brain Cortical Cells.
International journal of molecular sciences
Varlamova EG,Gudkov SV,Plotnikov EY,Turovsky EA
MA5-11757 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to study the effects of different-sized SeNPs on brain cells during oxygen-glucose deprivation.
Tue Jul 05 00:00:00 UTC 2022
Modulation Effects of Eugenol on Nephrotoxicity Triggered by Silver Nanoparticles in Adult Rats.
Biology
Aboelwafa HR,Ramadan RA,Ibraheim SS,Yousef HN
Published figure using Bcl-2 monoclonal antibody (Product # MA5-11757) in Immunohistochemistry
Sun Nov 27 00:00:00 UTC 2022
Development of New Natural Lipid-Based Nanoparticles Loaded with Aluminum-Phthalocyanine for Photodynamic Therapy against Melanoma.
Nanomaterials (Basel, Switzerland)
Mello VC,Araújo VHS,de Paiva KLR,Simões MM,Marques DC,da Silva Costa NR,de Souza IF,da Silva PB,Santos I,Almeida R,Magalhães KG,da Silva SW,Santos AS,Veiga-Souza F,Souza PEN,Raddichi MA,Longo JPF,de Araújo JTC,Muehlmann LA,Chorilli M,Báo SN
Published figure using Bcl-2 monoclonal antibody (Product # MA5-11757) in Western Blot
Tue Oct 11 00:00:00 UTC 2022
Calcium fructoborate regulate colon cancer (Caco-2) cytotoxicity through modulation of apoptosis.
Journal of biochemical and molecular toxicology
Kisacam MA,Ambarcioglu P,Yakan A
MA5-11757 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to indicate that CaFB treatment at 10 mM concentration, the IC50 dose found in our study, might prevent colon cancer cell proliferation both by inducing apoptosis and presumably by activating autophagy.
Sun May 01 00:00:00 UTC 2022
The Anti-Melanoma Effect of Betulinic Acid Functionalized Gold Nanoparticles: A Mechanistic In Vitro Approach.
Pharmaceuticals (Basel, Switzerland)
Ghiulai R,Mioc A,Racoviceanu R,Mioc M,Milan A,Prodea A,Semenescu A,Dehelean C,Barbu Tudoran L,Avram Ș,Trandafirescu C,Șoica C
MA5-11757 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to propose a biological in vitro assessment of betulinic acid (BA)-functionalized GNP.
Sat Nov 05 00:00:00 UTC 2022
miR-431-5p regulates apoptosis of cardiomyocytes after acute myocardial infarction via targeting selenoprotein T.
Physiological research
Geng H,Chen L,Su Y,Xu Q,Fan M,Huang R,Li X,Lu X,Pan M
MA5-11757 was used in Western Blotting to show that the expression of miR-431-5p in AMI myocardial tissues and H/R-induced HL-1 cardiomyocytes was significantly increased.
Fri Mar 25 00:00:00 UTC 2022
Long non-coding RNA TP73-AS1 promotes pancreatic cancer growth and metastasis through miRNA-128-3p/GOLM1 axis.
World journal of gastroenterology
Wang B,Sun X,Huang KJ,Zhou LS,Qiu ZJ
Published figure using Bcl-2 monoclonal antibody (Product # MA5-11757) in Western Blot
Fri May 07 00:00:00 UTC 2021
Acetone Extract of Cornus officinalis Leaves Exerts Anti-Melanoma Effects via Inhibiting STAT3 Signaling.
OncoTargets and therapy
Xu R,Zeng M,Wu Y,Wang S,Zhang B,Zhang J,Kan Y,Li B,Cao B,Zheng X,Feng W
MA5-11757 was used in Western Blot to investigate the intervention and mechanism of 50% acetone extract of C. officinalis leaves (SZYY) on melanoma xenografts.
Sat Apr 23 00:00:00 UTC 2022
Acetone Extract of Cornus officinalis Leaves Exerts Anti-Melanoma Effects via Inhibiting STAT3 Signaling.
OncoTargets and therapy
Xu R,Zeng M,Wu Y,Wang S,Zhang B,Zhang J,Kan Y,Li B,Cao B,Zheng X,Feng W
MA5-11757 was used in Western Blot to investigate the intervention and mechanism of 50% acetone extract of C. officinalis leaves (SZYY) on melanoma xenografts.
Sat Apr 23 00:00:00 UTC 2022
Pristimerin inhibits neuronal inflammation and protects cognitive function in mice with sepsis-induced brain injuries by regulating PI3K/Akt signalling.
Pharmaceutical biology
Xue W,Li Y,Zhang M
MA5-11757 was used in Western Blot to explore whether pristimerin protected against cognitive dysfunction and neuroinflammation in C57BL/6 J mice with sepsis-induced brain injuries.
Wed Dec 01 00:00:00 UTC 2021
Pristimerin inhibits neuronal inflammation and protects cognitive function in mice with sepsis-induced brain injuries by regulating PI3K/Akt signalling.
Pharmaceutical biology
Xue W,Li Y,Zhang M
MA5-11757 was used in Western Blot to explore whether pristimerin protected against cognitive dysfunction and neuroinflammation in C57BL/6 J mice with sepsis-induced brain injuries.
Wed Dec 01 00:00:00 UTC 2021
Circular RNA_0000629 Suppresses Bladder Cancer Progression Mediating MicroRNA-1290/CDC73.
Cancer management and research
Wang J,Luo J,Wu X,Gao Z
MA5-11757 was used in Western Blot to demonstrate that Circ_0000629 promotes the expression of CDC73 by competitively binding to miR-1290, thereby inhibiting the growth and metastasis of BC cells.
Thu Apr 21 00:00:00 UTC 2022
Circular RNA_0000629 Suppresses Bladder Cancer Progression Mediating MicroRNA-1290/CDC73.
Cancer management and research
Wang J,Luo J,Wu X,Gao Z
MA5-11757 was used in Western Blot to demonstrate that Circ_0000629 promotes the expression of CDC73 by competitively binding to miR-1290, thereby inhibiting the growth and metastasis of BC cells.
Thu Apr 21 00:00:00 UTC 2022
Human Adipose-derived mesenchymal stem cells promote lymphocyte apoptosis and alleviate atherosclerosis via miR-125b-1-3p/BCL11B signal axis.
Annals of palliative medicine
Yu C,Tang W,Lu R,Tao Y,Ren T,Gao Y
MA5-11757 was used in Western Blot to show that miR-125b-1-3p was expressed in hMSCs-Ad exosomes and can promote T lymphocyte apoptosis and alleviate AS by down-regulating BCL11B expression.
Mon Feb 01 00:00:00 UTC 2021
MYBL2 in synergy with CDC20 promotes the proliferation and inhibits apoptosis of gastric cancer cells.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University
Deng Q,Wu L,Li Y,Zou L
MA5-11757 was used in Western Blot to examine the role of myeloblastosis viral oncogene homolog-like 2 (MYBL2) in gastric cancer progression and investigate the underlying mechanisms.
Wed Sep 01 00:00:00 UTC 2021
Circ_CLASP2 Regulates High Glucose-Induced Dysfunction of Human Endothelial Cells Through Targeting miR-140-5p/FBXW7 Axis.
Frontiers in pharmacology
Zhang Q,Long J,Li N,Ma X,Zheng L
MA5-11757 was used in Western Blot to suggest that the overexpression of circ_CLASP2 protected HUVEC from HG-induced dysfunction at least partly through the regulation of the miR-140-5p/FBXW7 axis.
Tue Mar 30 00:00:00 UTC 2021
Circ_CLASP2 Regulates High Glucose-Induced Dysfunction of Human Endothelial Cells Through Targeting miR-140-5p/FBXW7 Axis.
Frontiers in pharmacology
Zhang Q,Long J,Li N,Ma X,Zheng L
MA5-11757 was used in Western Blot to suggest that the overexpression of circ_CLASP2 protected HUVEC from HG-induced dysfunction at least partly through the regulation of the miR-140-5p/FBXW7 axis.
Tue Mar 30 00:00:00 UTC 2021
LncRNA ASAP1-IT1 enhances cancer cell stemness via regulating miR-509-3p/YAP1 axis in NSCLC.
Cancer cell international
Liu Y,Yang Y,Zhang L,Lin J,Li B,Yang M,Li H,Chen K,Zhao W
MA5-11757 was used in Western Blot to show that the level of YAP1 was regulated by ASAP1-IT1 and miR-509-3p.
Fri Oct 29 00:00:00 UTC 2021
LncRNA ASAP1-IT1 enhances cancer cell stemness via regulating miR-509-3p/YAP1 axis in NSCLC.
Cancer cell international
Liu Y,Yang Y,Zhang L,Lin J,Li B,Yang M,Li H,Chen K,Zhao W
MA5-11757 was used in Western Blot to show that the level of YAP1 was regulated by ASAP1-IT1 and miR-509-3p.
Fri Oct 29 00:00:00 UTC 2021
CCNB1 Expedites the Progression of Cervical Squamous Cell Carcinoma via the Regulation by FOXM1.
OncoTargets and therapy
Li S,Liu N,Piao J,Meng F,Li Y
MA5-11757 was used in Western Blotting to explore the mechanism underlying CCNB1 regulation on cell cycle progression in cervical squamous cell carcinoma.
Mon Oct 24 00:00:00 UTC 2022
CCNB1 Expedites the Progression of Cervical Squamous Cell Carcinoma via the Regulation by FOXM1.
OncoTargets and therapy
Li S,Liu N,Piao J,Meng F,Li Y
MA5-11757 was used in Western Blotting to explore the mechanism underlying CCNB1 regulation on cell cycle progression in cervical squamous cell carcinoma.
Mon Oct 24 00:00:00 UTC 2022
Desoxyrhapontigenin attenuates neuronal apoptosis in an isoflurane-induced neuronal injury model by modulating the TLR-4/cyclin B1/Sirt-1 pathway.
AMB Express
Liang F,Fu X,Li Y,Han F
Published figure using Bcl-2 monoclonal antibody (Product # MA5-11757) in Western Blot
Wed Sep 30 00:00:00 UTC 2020
MiR-33a-5p inhibits the growth and metastasis of melanoma cells by targeting SNAI2.
Neoplasma
Zhang ZR,Yang N
MA5-11757 was used in Western Blotting to study how miR-33a-5p repressed the progression of melanoma by targeting SNAI2 via inactivation of the PI3K/AKT/mTOR signaling pathway, providing a potential molecular mechanism for the treatment of melanoma.
Wed Jul 01 00:00:00 UTC 2020
Silencing of soluble epoxide hydrolase 2 gene reduces H2O2-induced oxidative damage in rat intestinal epithelial IEC-6 cells via activating PI3K/Akt/GSK3β signaling pathway.
Cytotechnology
Li J,Luo J,Zhang Y,Tang C,Wang J,Chen C
MA5-11757 was used in Western Blotting to explore the effects and molecular mechanism of siEPHX2 on H2O2-induced oxidative damage in rat intestinal epithelial IEC-6 cells.
Sat Feb 01 00:00:00 UTC 2020
MiR-203-3p inhibits the oxidative stress, inflammatory responses and apoptosis of mice podocytes induced by high glucose through regulating Sema3A expression.
Open life sciences
Chen J,Xu Q,Zhang W,Zhen Y,Cheng F,Hua G,Lan J,Tu C
MA5-11757 was used in Western Blot to reveal that miR-203-3p alleviated the podocyte injury induced by HG via regulating Sema3A expression.
Tue Apr 06 00:00:00 UTC 2021
MiR-203-3p inhibits the oxidative stress, inflammatory responses and apoptosis of mice podocytes induced by high glucose through regulating Sema3A expression.
Open life sciences
Chen J,Xu Q,Zhang W,Zhen Y,Cheng F,Hua G,Lan J,Tu C
MA5-11757 was used in Western Blot to reveal that miR-203-3p alleviated the podocyte injury induced by HG via regulating Sema3A expression.
Tue Apr 06 00:00:00 UTC 2021
Therapeutic Potentials of Selected Antihypertensive Agents and Their Fixed-Dose Combinations Against Trastuzumab-Mediated Cardiotoxicity.
Frontiers in pharmacology
Olorundare OE,Adeneye AA,Akinsola AO,Ajayi AM,Agede OA,Soyemi SS,Mgbehoma AI,Okoye II,Albrecht RM,Ntambi JM,Crooks PA
Published figure using Bcl-2 monoclonal antibody (Product # MA5-11757) in Immunohistochemistry
Wed Apr 28 00:00:00 UTC 2021
MicroRNA-325-3p Facilitates Immune Escape of Mycobacterium tuberculosis through Targeting LNX1 via NEK6 Accumulation to Promote Anti-Apoptotic STAT3 Signaling.
mBio
Fu B,Xue W,Zhang H,Zhang R,Feldman K,Zhao Q,Zhang S,Shi L,Pavani KC,Nian W,Lin X,Wu H
MA5-11757 was used in Western Blotting to contribution to the understanding of the immune escape of M. tuberculosis, and they provide a theoretical basis for the development of therapeutic approaches for drug-resistant TB.
Tue Jun 02 00:00:00 UTC 2020
MicroRNA-325-3p Facilitates Immune Escape of Mycobacterium tuberculosis through Targeting LNX1 via NEK6 Accumulation to Promote Anti-Apoptotic STAT3 Signaling.
mBio
Fu B,Xue W,Zhang H,Zhang R,Feldman K,Zhao Q,Zhang S,Shi L,Pavani KC,Nian W,Lin X,Wu H
MA5-11757 was used in Western Blotting to contribution to the understanding of the immune escape of M. tuberculosis, and they provide a theoretical basis for the development of therapeutic approaches for drug-resistant TB.
Tue Jun 02 00:00:00 UTC 2020
Pulsed focused ultrasound enhances the therapeutic effect of mesenchymal stromal cell-derived extracellular vesicles in acute kidney injury.
Stem cell research & therapy
Ullah M,Liu DD,Rai S,Razavi M,Concepcion W,Thakor AS
MA5-11757 was used in Western Blotting to show that pFUS may be a strategy for enhancing the therapeutic efficacy of MSC-derived EV treatment for the treatment of AKI.
Mon Sep 14 00:00:00 UTC 2020
Pulsed focused ultrasound enhances the therapeutic effect of mesenchymal stromal cell-derived extracellular vesicles in acute kidney injury.
Stem cell research & therapy
Ullah M,Liu DD,Rai S,Razavi M,Concepcion W,Thakor AS
MA5-11757 was used in Western Blotting to show that pFUS may be a strategy for enhancing the therapeutic efficacy of MSC-derived EV treatment for the treatment of AKI.
Mon Sep 14 00:00:00 UTC 2020
Ameliorative effect of urolithin A on d-gal-induced liver and kidney damage in aging mice via its antioxidative, anti-inflammatory and antiapoptotic properties.
RSC advances
Chen P,Lei J,Chen F,Zhou B
MA5-11757 was used in Western Blotting to suggest that Uro A ameliorated d-gal-induced liver and kidney injury through attenuating oxidative stress, inflammatory responses and apoptosis.
Mon Feb 24 00:00:00 UTC 2020
Silencing of heat shock protein 27 increases the radiosensitivity of non‑small cell lung carcinoma cells.
Molecular medicine reports
Xu L,Lin X,Zheng Y,Zhou H
MA5-11757 was used in Western Blotting to study the role of HSPB1 in NSCLC cells induced by radiation.
Mon Jul 01 00:00:00 UTC 2019
Silencing of heat shock protein 27 increases the radiosensitivity of non‑small cell lung carcinoma cells.
Molecular medicine reports
Xu L,Lin X,Zheng Y,Zhou H
MA5-11757 was used in Western Blotting to study the role of HSPB1 in NSCLC cells induced by radiation.
Mon Jul 01 00:00:00 UTC 2019
Parthenolide inhibits the proliferation and induces the apoptosis of human uveal melanoma cells.
International journal of ophthalmology
Che ST,Bie L,Li X,Qi H,Yu P,Zuo L
MA5-11757 was used in Western Blotting to deduce that human uveal melanoma cell proliferation can be inhibited and apoptosis induced by parthenolide through the arrest of G1 phase and regulation of the mitochondrial pathway.
Thu Oct 01 00:00:00 UTC 2020
The Potential Impact of Connexin 43 Expression on Bcl-2 Protein Level and Taxane Sensitivity in Head and Neck Cancers-In Vitro Studies.
Cancers
Gurbi B,Brauswetter D,Varga A,Gyulavári P,Pénzes K,Murányi J,Zámbó V,Birtalan E,Krenács T,Becker DL,Csala M,Vályi-Nagy I,Peták I,Dános K
Published figure using Bcl-2 monoclonal antibody (Product # MA5-11757) in Immunofluorescence
Fri Nov 22 00:00:00 UTC 2019
Simvastatin Induces Apoptosis in Medulloblastoma Brain Tumor Cells via Mevalonate Cascade Prenylation Substrates.
Cancers
Sheikholeslami K,Ali Sher A,Lockman S,Kroft D,Ganjibakhsh M,Nejati-Koshki K,Shojaei S,Ghavami S,Rastegar M
MA5-11757 was used in Western Blotting to suggests the potential application of a novel non-classical adjuvant therapy for medulloblastoma, through the regulation of protein prenylation intermediates that occurs via inhibition of the mevalonate pathway.
Wed Jul 17 00:00:00 UTC 2019
LINC00152 promotes the proliferation of gastric cancer cells by regulating B-cell lymphoma-2.
Journal of cellular biochemistry
Mao Y,Tie Y,Du J,He J
MA5-11757 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to reveal that LINC00152 was overexpressed in tissues, serum, and PBMCs of patients with gastric cancer.
Fri Mar 01 00:00:00 UTC 2019
Melittin induces NSCLC apoptosis via inhibition of miR-183.
OncoTargets and therapy
Gao D,Zhang J,Bai L,Li F,Dong Y,Li Q
MA5-11757 was used in Western Blotting to evaluate the effect of melittin on non-small cell lung cancer.
Fri Mar 18 00:00:00 UTC 2022
The protective effects of total paeony glycoside on ischemia/reperfusion injury in H9C2 cells via inhibition of the PI3K/Akt signaling pathway.
Molecular medicine reports
Shen P,Chen J,Pan M
Published figure using Bcl-2 monoclonal antibody (Product # MA5-11757) in Western Blot
Sat Sep 01 00:00:00 UTC 2018
Combined effects of octreotide and cisplatin on the proliferation of side population cells from anaplastic thyroid cancer cell lines.
Oncology letters
Li Z,Jiang X,Chen P,Wu X,Duan A,Qin Y
MA5-11757 was used in Western Blotting to suggest that combined treatment with octreotide and cisplatin induces anaplastic thyroid cancer cell apoptosis and suppresses cell proliferation.
Sat Sep 01 00:00:00 UTC 2018
Sunset Yellow and Allura Red modulate Bcl2 and COX2 expression levels and confer oxidative stress-mediated renal and hepatic toxicity in male rats.
PeerJ
Khayyat LI,Essawy AE,Sorour JM,Soffar A
MA5-11757 was used in Immunohistochemistry to investigate the possible toxic effect of two types of widely used food additives, Sunset Yellow and Allura Red, by assessing the physiological, histopathological and ultrastructural changes in the liver and kidney.
Thu Oct 01 00:00:00 UTC 2020
Immunoexpression of vascular endothelial growth factor and B-cell lymphoma 2 in the uterine tissue of rats treated with melatonin in the estrus phase1.
Acta cirurgica brasileira
Görük NY,Deveci E
MA5-11757 was used in Immunohistochemistry to demonstrate that the increase in vascular endothelial growth factor expression results in rearrangement of endothelial cell growth and induces angiogenesis.
Sun Jul 01 00:00:00 UTC 2018
Induction of apoptosis and suppression of tumor growth by Nur77-derived Bcl-2 converting peptide in chemoresistant lung cancer cells.
Oncotarget
Pearce MC,Gamble JT,Kopparapu PR,O'Donnell EF,Mueller MJ,Jang HS,Greenwood JA,Satterthwait AC,Tanguay RL,Zhang XK,Kolluri SK
Published figure using Bcl-2 monoclonal antibody (Product # MA5-11757) in Flow Cytometry
Fri May 25 00:00:00 UTC 2018
Lactobacillus casei Strain Shirota Enhances the In Vitro Antiproliferative Effect of Geniposide in Human Oral Squamous Carcinoma HSC-3 Cells.
Molecules (Basel, Switzerland)
Qian Y,Song JL,Sun P,Yi R,Liu H,Feng X,Park KY,Zhao X
MA5-11757 was used in Western Blotting to investigate the enhanced anti-proliferative effect of Lactobacillus casei strain Shirota on geniposide actions in human oral squamous carcinoma HSC-3 cells.
Thu May 03 00:00:00 UTC 2018
The role of immunohistochemical adrenomedullin and Bcl-2 expression in development of type-1 endometrial adenocarcinoma: Adrenomedullin expression in endometrium.
Pathology, research and practice
Bozkurt KK,Yalçın Y,Erdemoğlu E,Tatar B,Erdemoğlu E,Çerçi SS,Çiriş İM,Başpınar Ş,Uğuz A,Kapucuoğlu N
MA5-11757 was used in immunohistochemistry - paraffin section to study the development of type-1 endometrial adenocarcinoma and the role of Bcl-2 expression and immunohistochemical adrenomedullin in the endometrium
Sun May 01 00:00:00 UTC 2016
Expression of Cox-2 and Bcl-2 in Paget's disease of the breast.
Asian Pacific journal of cancer prevention : APJCP
Alikanoglu AS,Yildirim M,Suren D,Tutus B,Kaya V,Topal CS,Keser S,Karadayi AN,Kapucuoglu FN,Ayva S,Gunduz S
MA5-11757 was used in immunohistochemistry - paraffin section to examine Cox-2 and bcl-2 expression in the development of Paget's disease
Tue Dec 08 00:00:00 UTC 2015
Impact of Diverse Immune Evasion Mechanisms of Cancer Cells on T Cells Engaged by EpCAM/CD3-Bispecific Antibody Construct AMG 110.
PloS one
Deisting W,Raum T,Kufer P,Baeuerle PA,Münz M
MA5-11757 was used in flow cytometry and western blot to study the use of bispecific T cell engager
Thu Jun 16 00:00:00 UTC 2016
Association of increased osteopontin and splice variant-c mRNA expression with HER2 and triple-negative/basal-like breast carcinomas subtypes and recurrence.
Human pathology
Ortiz-Martínez F,Perez-Balaguer A,Ciprián D,Andrés L,Ponce J,Adrover E,Sánchez-Payá J,Aranda FI,Lerma E,Peiró G
MA5-11757 was used in immunohistochemistry to study the expression of osteopontin and osteopontin-c in breast cancer and the association with aggressive subtypes and a high risk of recurrence
Sat Mar 01 00:00:00 UTC 2014
The relation of beclin 1 and bcl-2 expressions in high grade prostatic intraepithelial neoplasia and prostate adenocarcinoma: a tissue microarray study.
Pathology, research and practice
Baspinar S,Bircan S,Orhan H,Kapucuoglu N,Bozkurt KK
MA5-11757 was used in immunohistochemistry - paraffin section to assess beclin 1 and bcl-2 expression and investigate their relationship with clinicopathological parameters of prostate cancer and high grade prostatic intraepithelial neoplasia
Tue Jul 01 00:00:00 UTC 2014
Tissue biomarkers in prognostication of serous ovarian cancer following neoadjuvant chemotherapy.
BioMed research international
Khandakar B,Mathur SR,Kumar L,Kumar S,Datta Gupta S,Iyer VK,Kalaivani M
MA5-11757 was used in immunohistochemistry to attempt to identify prognostic biomarkers in serous ovarian cancer patients treated with neoadjuvant chemotherapy
Mon Jan 19 00:00:00 UTC 2015
New diagnostic markers in salivary gland tumors.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Schneider S,Kloimstein P,Pammer J,Brannath W,Grasl MCh,Erovic BM
MA5-11757 was used in immunohistochemistry to study the expresion of tumor antigens in order to identify novel diagnostic markers of parotid gland tumors
Tue Jul 01 00:00:00 UTC 2014
BCL2, BCL6, IGH, TP53, and MYC protein expression and gene rearrangements as prognostic markers in diffuse large B-cell lymphoma: a study of 44 Turkish patients.
Cancer genetics
Akay OM,Aras BD,Isiksoy S,Toprak C,Mutlu FS,Artan S,Oner U,Gulbas Z
MA5-11757 was used in immunohistochemistry to study the prognostic value of immunohistochemical and FISH analysis of BCL2, BCL6, IGH, TP53, and MYC in Turkish patients with diffuse large B-cell lymphoma
Sat Mar 01 00:00:00 UTC 2014
The protective effects of carnosine in alcohol-induced hepatic injury in rats.
Toxicology and industrial health
Baykara B,Micili SC,Tugyan K,Tekmen I,Bagriyanik H,Sonmez U,Sonmez A,Oktay G,Yener N,Ozbal S
MA5-11757 was used in immunohistochemistry to study the mechanisms underlying the protective effects of carnosine in a rat model of alcohol-induced liver damage
Sat Feb 01 00:00:00 UTC 2014
Association of RASSF1A and p63 with poor recurrence-free survival in node-negative stage I-II non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
Ko E,Lee BB,Kim Y,Lee EJ,Cho EY,Han J,Shim YM,Park J,Kim DH
MA5-11757 was used in immunohistochemistry to study the value of RASSF1A and p63 alterations in predicting node-negative stage I-II non-small cell lung cancer recurrence-free survival
Fri Mar 01 00:00:00 UTC 2013
Effect of blueberry pretreatment on diethylnitrosamine-induced oxidative stress and liver injury in rats.
Environmental toxicology and pharmacology
Bingül İ,Başaran-Küçükgergin C,Tekkeşin MS,Olgaç V,Doğru-Abbasoğlu S,Uysal M
MA5-11757 was used in immunohistochemistry to study the mechanisms underlying the beneficial effects of pre-treatment with bluberries on diethylnitrosamine-induced liver injury in rats
Sun Sep 01 00:00:00 UTC 2013
Identification of novel target proteins in sebaceous gland carcinoma.
Head & neck
Erovic BM,Al Habeeb A,Harris L,Goldstein DP,Kim D,Ghazarian D,Irish JC
MA5-11757 was used in immunohistochemistry to identify novel therapeutic target proteins in sebaceous gland carcinoma
Wed May 01 00:00:00 UTC 2013
The effects of ulipristal on Bax/Bcl-2, cytochrome c, Ki-67 and cyclooxygenase-2 expression in a rat model with surgically induced endometriosis.
European journal of obstetrics, gynecology, and reproductive biology
Huniadi CA,Pop OL,Antal TA,Stamatian F
MA5-11757 was used in immunohistochemistry to use a rat model of endometriosis to study the effects of ulipristal on endometrial histology and the expression of Bax/Bcl-2, cytochrome c, Ki-67 and COX-2
Mon Jul 01 00:00:00 UTC 2013
Apoptosis through regulation of Bcl-2, Bax and Mcl-1 expressions in endometriotic cyst lesions and the endometrium of women with moderate to severe endometriosis.
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
Korkmaz D,Bastu E,Dural O,Yasa C,Yavuz E,Buyru F
MA5-11757 was used in immunohistochemistry to study the role of apoptosis in endometriosis pathophysiology by examining endometrionic cyst lesions and patient endometrium for the expression of Bcl-2, Bax and Mcl-1
Tue Oct 01 00:00:00 UTC 2013
Inhibition of proliferation and induction of autophagy by atorvastatin in PC3 prostate cancer cells correlate with downregulation of Bcl2 and upregulation of miR-182 and p21.
PloS one
Peng X,Li W,Yuan L,Mehta RG,Kopelovich L,McCormick DL
MA5-11757 was used in western blot to study the involvement of Bcl-2, miRNA-182 and p21 in the mechanism by which atorvastatin induces autophagy and inhibits the growth of prostate cancer cells
Tue Mar 18 00:00:00 UTC 2014
miR-129 promotes apoptosis and enhances chemosensitivity to 5-fluorouracil in colorectal cancer.
Cell death & disease
Karaayvaz M,Zhai H,Ju J
MA5-11757 was used in western blot to study the potential tumor suppressor activity of miRNA-129 and its role in promoting 5-fluorouracil sensitivity in colorectal cancer
Thu Jun 06 00:00:00 UTC 2013
Pericardial synovial sarcoma, a potential for misdiagnosis: clinicopathologic and molecular cytogenetic analysis of three cases with literature review.
American journal of clinical pathology
Cheng Y,Sheng W,Zhou X,Wang J
MA5-11757 was used in immunohistochemistry to report on three cases of pericardial synovial sarcoma
Sun Jan 01 00:00:00 UTC 2012
Biomarkers of parathyroid carcinoma.
Endocrine pathology
Erovic BM,Harris L,Jamali M,Goldstein DP,Irish JC,Asa SL,Mete O
MA5-11757 was used in immunohistochemistry to establish a biomarker panel suitable for the identification of parathyroid carcinomas
Sat Dec 01 00:00:00 UTC 2012
Prognostic and predictive markers in medullary thyroid carcinoma.
Endocrine pathology
Erovic BM,Kim D,Cassol C,Goldstein DP,Irish JC,Asa SL,Mete O
MA5-11757 was used in immunohistochemistry to identify markers with progniostic and predictive value in patients with medullary thyroid cancer
Sat Dec 01 00:00:00 UTC 2012
Prognostic value of oncoprotein expressions in thyroid papillary carcinoma.
Medical oncology (Northwood, London, England)
Balta AZ,Filiz AI,Kurt Y,Sucullu I,Yucel E,Akin ML
MA5-11757 was used in immunohistochemistry to identify the relationship between oncoprotein expression and clinical symptoms of carcinoma
Fri Jun 01 00:00:00 UTC 2012
Effect of different durations of overdistention on rat bladder function and morphology.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
Jin XD,Cao M,Zhou XL,Yin HP,Chen ZD,Xu N,Jiang H
MA5-11757 was used in western blot to study changes in urinary bladder function and morphology following different periods of overdistension and the molecular mechanisms involved
Mon Oct 01 00:00:00 UTC 2012
Prohibitin induces apoptosis in BGC823 gastric cancer cells through the mitochondrial pathway.
Asian Pacific journal of cancer prevention : APJCP
Zhang L,Ji Q,Ni ZH,Sun J
MA5-11757 was used in western blot to study the role of the mitochondrial pathway in the mechanism by which prohibitin induces gastric cancer cell apoptosis
Thu Apr 18 00:00:00 UTC 2013
Resveratrol attenuates doxorubicin-induced cellular damage by modulating nitric oxide and apoptosis.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie
Oktem G,Uysal A,Oral O,Sezer ED,Olukman M,Erol A,Akgur SA,Bilir A
MA5-11757 was used in immunohistochemistry to study the mechanism by which resveratrol attenuates doxorubicin-induced cellular damage
Sun Jul 01 00:00:00 UTC 2012
A unique case of follicular lymphoma provides insights to the clonal evolution from follicular lymphoma in situ to manifest follicular lymphoma.
Blood
Bonzheim I,Salaverria I,Haake A,Gastl G,Adam P,Siebert R,Fend F,Quintanilla-Martinez L
MA5-11757 was used in immunohistochemistry to investigate the progression of follicular lymphoma in situ
Thu Sep 22 00:00:00 UTC 2011
P53, bcl-2, and nm23 expressions in serous ovarian tumors: correlation with the clinical and histopathological parameters.
Turk patoloji dergisi
Arik D,Kulaçoğlu S
MA5-11757 was used in immunohistochemistry to study the diagnostic value of p53, bcl-2 and nm23 in serous ovarian tumors
Sat Jan 01 00:00:00 UTC 2011
Heme oxygenase-1 prevents hyperthyroidism induced hepatic damage via an antioxidant and antiapoptotic pathway.
The Journal of surgical research
Giriş M,Erbil Y,Depboylu B,Mete O,Türkoğlu U,Abbasoğlu SD,Uysal M
MA5-11757 was used in immunohistochemistry to investigate the protective effect of heme oxygenase-1 against hyperthyroidism and its mechanism
Wed Dec 01 00:00:00 UTC 2010
Reduced protection from simian immunodeficiency virus SIVmac251 infection afforded by memory CD8+ T cells induced by vaccination during CD4+ T-cell deficiency.
Journal of virology
Vaccari M,Mattapallil J,Song K,Tsai WP,Hryniewicz A,Venzon D,Zanetti M,Reimann KA,Roederer M,Franchini G
MA5-11757 was used in Flow cytometry/Cell sorting to support the notion that adaptive CD4(+) T cells are critical for the generation of effective CD8(+) T-cell responses to SIV that, in turn, contribute to protection from AIDS.
Wed Oct 01 00:00:00 UTC 2008
Cyclooxygenase-2 induces genomic instability, BCL2 expression, doxorubicin resistance, and altered cancer-initiating cell phenotype in MCF7 breast cancer cells.
The Journal of surgical research
Singh B,Cook KR,Vincent L,Hall CS,Berry JA,Multani AS,Lucci A
MA5-11757 was used in western blot to examine the role of cyclooxygenase-2 in breast cancer sensitivity towards treatment
Sun Jun 15 00:00:00 UTC 2008
Immunohistochemical expression of apoptosis regulating proteins and sex hormone receptors in meningiomas.
Neuropathology : official journal of the Japanese Society of Neuropathology
Takei H,Buckleair LW,Powell SZ
MA5-11757 was used in immunohistochemistry - paraffin section to define the relationship between progesterone receptor and Bcl-2 in meningiomas
Fri Feb 01 00:00:00 UTC 2008
Increased expression of CCAAT/enhancer-binding protein beta in proliferative inflammatory atrophy of the prostate: relation with the expression of COX-2, the androgen receptor, and presence of focal chronic inflammation.
The Prostate
Wang W,Bergh A,Damber JE
MA5-11757 was used in immunohistochemistry to study the mechanisms driving increased expression of C/EBPbeta in proliferative inflammatory atrophy of the prostate
Wed Aug 01 00:00:00 UTC 2007
Lymphoma-like lesion of the uterine cervix: report of 12 cases of a rare entity.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
Ma J,Shi QL,Zhou XJ,Meng K,Chen JY,Huang WB
MA5-11757 was used in immunohistochemistry to investigate the clinicopathologic features of 12 clinical cases of lymphoma-like lesions of the uterine cervix
Sun Apr 01 00:00:00 UTC 2007
The correlation between the immunostains for p53 and Ki67 with bcl-2 expression and classical prognostic factors in colorectal carcinomas.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
Gurzu S,Jung J,Mezei T,Pávai Z
MA5-11757 was used in immunohistochemistry to study p53 and Ki67 status and their relationship with bcl-2 expression and classical prognostic factors in colorectal carcinoma
Wed Jan 16 00:00:00 UTC 2008
Expression of caspase-3, p53 and Bcl-2 in generalized aggressive periodontitis.
Head & face medicine
Bulut S,Uslu H,Ozdemir BH,Bulut OE
MA5-11757 was used in immunohistochemistry to study the expression of caspase-3, p53 and Bcl-2 in generalized aggressive periodontitis
Tue Jun 20 00:00:00 UTC 2006
Expression of Bcl-2 and Ki-67 in tamoxifen-associated endometrial polyps: comparison with postmenopausal polyps.
Onkologie
Altaner S,Gucer F,Tokatli F,Guresci S,Ozdemir C,Puyan FO,Kutlu K
MA5-11757 was used in immunohistochemistry to compare the expression of Bcl-2 and ki-67 in tamoxifen-associated endometrial polyps and post-menopausal polyps
Fri Sep 01 00:00:00 UTC 2006
Bcl-2 expression predicts radiotherapy failure in laryngeal cancer.
British journal of cancer
Nix P,Cawkwell L,Patmore H,Greenman J,Stafford N
MA5-11757 was used in immunohistochemistry to study the value of Bcl-2 expression in predicting the response to radiotherapy of laryngeal cancer patients
Mon Jun 20 00:00:00 UTC 2005
Irreversible pan-ErbB tyrosine kinase inhibitor CI-1033 induces caspase-independent apoptosis in colorectal cancer DiFi cell line.
Apoptosis : an international journal on programmed cell death
Skvortsov S,Skvortsova I,Sarg B,Loeffler-Ragg J,Lindner H,Lukas P,Tabernero J,Zwierzina H
MA5-11757 was used in western blot to investigate the effect of pan-ErbB tyrosine kinase inhibitor CI-1033 on colorectal cancer cell apoptosis
Sat Oct 01 00:00:00 UTC 2005
Downregulation of Bcl-2 by podocytes is associated with progressive glomerular injury and clinical indices of poor renal prognosis in human IgA nephropathy.
Journal of the American Society of Nephrology : JASN
Qiu LQ,Sinniah R,I-Hong Hsu S
MA5-11757 was used in immunohistochemistry to investigate the influence of Bcl-2 reduction on the progression and prognosis of human IgA nephropathy
Thu Jan 01 00:00:00 UTC 2004
