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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Beclin 1 Antibodies

          Proteintech

          Beclin 1 Polyclonal Antibody

          815 References
          View all (69) Beclin 1 antibodies
          Datasheet
          Protocols
          Questions & Answers
          Datasheet
          Protocols
          Questions & Answers

          Cite Beclin 1 Polyclonal Antibody

          • Antibody Testing Data (33)
          Beclin 1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          Beclin 1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 33

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          Beclin 1 Antibody (11306-1-AP) in ICC/IF

          Immunofluorescent analysis of NIH/3T3 cells using 11306-1-AP (Beclin 1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Beclin 1 Antibody in Immunocytochemistry (ICC/IF)
          Beclin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Beclin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Beclin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Beclin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Beclin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Beclin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Beclin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Beclin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Beclin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Beclin 1 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          Beclin 1 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          Beclin 1 Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          Beclin 1 Antibody in Western Blot (WB)
          Beclin 1 Antibody in Western Blot (WB)
          Beclin 1 Antibody in Western Blot (WB)
          Beclin 1 Antibody in Western Blot (WB)
          Beclin 1 Antibody in Western Blot (WB)
          Beclin 1 Antibody in Western Blot (WB)
          Beclin 1 Antibody in Western Blot (WB)
          Beclin 1 Antibody in Western Blot (WB)
          Beclin 1 Antibody in Western Blot (WB)
          Beclin 1 Antibody in Western Blot (WB)
          Beclin 1 Antibody in Western Blot (WB)
          Beclin 1 Antibody in Western Blot (WB)
          Beclin 1 Antibody in Western Blot (WB)
          Beclin 1 Antibody in Western Blot (WB)
          Beclin 1 Antibody in Western Blot (WB)
          Beclin 1 Antibody in Western Blot (WB)
          Beclin 1 Antibody in Western Blot (WB)
          Beclin 1 Antibody in Western Blot (WB)
          Beclin 1 Antibody in Western Blot (WB)
          Beclin 1 Antibody in Immunoprecipitation (IP)

          Product Details

          11306-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          View 649 publications 649 publications

          Immunohistochemistry (IHC)

          -
          View 85 publications 85 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunohistochemistry (PFA fixed) (IHC (PFA))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:20-1:200
          View 55 publications 55 publications

          Immunoprecipitation (IP)

          0.5-4.0 µg
          View 14 publications 14 publications

          Miscellaneous PubMed (MISC)

          -
          View 5 publications 5 publications

          Not applicable (N/A)

          -
          View 7 publications 7 publications
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Fish, Human, Mouse, Prawn, Rat, Zebrafish

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Beclin 1 Fusion Protein Ag1843 (141-450 aa encoded by BC010276)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: TDTLLDQLD TQLNVTENEC QNYKRCLEIL EQMNEDDSEQ LQMELKELAL EEERLIQELE DVEKNRKIVA ENLEKVQAEA ERLDQEEAQY QREYSEFKRQ QLELDDELKS VENQMRYAQT QLDKLKKTNV FNATFHIWHS GQFGTINNFR LGRLPSVPVE WNEINAAWGQ TVLLLHALAN KMGLKFQRYR LVPYGNHSYL ESLTDKSKEL PLYCSGGLRF FWDNKFDHAM VAFLDCVQQF KEEVEKGETR FCLPYRMDVE KGKIEDTGGS GGSYSIKTQF NSEEQWTKAL KFMLTNLKWG LAWVSSQFYN K (141-450 aa encoded by BC010276)

          Target Information

          Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: APG6; ATG6 autophagy related 6 homolog; Bcl-2-interacting protein beclin; beclin 1 (coiled-coil, moesin-like BCL2-interacting protein); beclin 1 (coiled-coil, myosin-like BCL2-interacting protein); beclin 1, autophagy related; Beclin-1; Coiled-coil myosin-like BCL2-interacting protein; coiled-coil, myosin-like BCL2-interacting protein; Protein GT197; testis secretory sperm-binding protein Li 215e

          View more View less

          Gene Aliases: 4921513J16Rik; 5430417M23Rik; ATG6; beclin1; BECN1; GT197; VPS30

          View more View less

          UniProt ID: (Human) Q14457, (Rat) Q91XJ1, (Mouse) O88597

          View more View less

          Entrez Gene ID: (Human) 8678, (Rat) 114558, (Mouse) 56208

          View more View less

          Function(s)
          protein binding ubiquitin protein ligase binding phosphatidylinositol 3-kinase binding molecular_function
          Process(es)
          autophagosome assembly cytokinesis response to hypoxia autophagy apoptotic process cellular defense response cellular response to nitrogen starvation lysosome organization mitotic metaphase plate congression negative regulation of cell proliferation positive regulation of autophagy positive regulation of phosphatidylinositol 3-kinase signaling macroautophagy positive regulation of macroautophagy CVT pathway regulation of cytokinesis receptor catabolic process response to vitamin E cellular response to glucose starvation response to drug negative regulation of apoptotic process engulfment of apoptotic cell nucleophagy late endosome to vacuole transport neuron development beta-amyloid metabolic process regulation of catalytic activity defense response to virus negative regulation of cell death cellular response to aluminum ion cellular response to epidermal growth factor stimulus mitophagy in response to mitochondrial depolarization positive regulation of attachment of mitotic spindle microtubules to kinetochore positive regulation of mitophagy negative regulation of reactive oxygen species metabolic process mitophagy response to other organism angiogenesis cell cycle cell division
          It has to be done as per old AB suggested Products section.
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