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Invitrogen
Beclin 1 Polyclonal Antibody
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FIGURE: 1 / 1
Beclin 1 Antibody (PA5-72236) in WB
Western blot analysis of Beclin 1 in various lysates. Samples were incubated with Beclin 1 polyclonal antibody (Product # PA5-72236) using a dilution of 1:2,000 followed by Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at a dilution of 1:10,000. Lysates/proteins: 20 µg per lane. Lane 1: Zebrafish lysates; Lane 2: ZF4 whole cell lysates. Predicted band size: 51 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Product Details
PA5-72236
Product Specifications
Species Reactivity
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 388-421 amino acids from the human region of DANRE becn1
Conjugate
Form
Liquid
Concentration
0.48 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2718090
Target Information
Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways - PI3KC3-C1 is involved in the initation of autophagosomes and PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis. Beclin 1 also plays a role in antiviral host defense.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: APG6; Beclin-1
Gene Aliases: becn1; zgc:73097
UniProt ID: (Zebrafish) F1RCP1
Entrez Gene ID: (Zebrafish) 393846
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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