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Bestrophin 2 Antibody (PA5-33363) in IHC (P)
Immunohistochemistry analysis of Bestrophin 2 in human Lymph Node, Non-Hodgkins Lymphoma. Samples were incubated with Bestrophin 2 polyclonal antibody (Product # PA5-33363). Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Product Details
PA5-33363
Product Specifications
Species Reactivity
Dog,
Human,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 15 amino acid peptide from internal region of human BEST2 / Bestrophin-2.
Conjugate
Form
Liquid
Concentration
0.9 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2550744
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Dog (100%) Mouse, Hamster, Panda, Bovine (93%) Opossum (87%).
Target Information
Best2 forms calcium-sensitive chloride channels and is permeable to bicarbonate. The Best2 gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in the Best2 gene is associated with vitelliform macular dystrophy. The Best2 gene is mainly expressed in the retinal pigment epithelium and colon. Diseases associated with BEST2 include Vitelliform Macular Dystrophy and Bestrophinopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bestrophin 2; Bestrophin-2a; Hbest2; vitelliform macular dystrophy 2-like 1; Vitelliform macular dystrophy 2-like protein 1; VMD2-like gene 1; VMD2L-1
Gene Aliases: BEST2; VMD2L1
UniProt ID: (Human) Q8NFU1
Entrez Gene ID: (Human) 54831, (Dog) 100856525
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