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Fabgennix
Bestrophin 3 Polyclonal Antibody
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FIGURE: 1 / 1
Bestrophin 3 Antibody (BEST-301AP) in IHC (P)
Mouse Glomerulus- Bestrophin 3 Primary Antibody: BEST-301AP; 1:100 dilution. PFA-fixed, paraffin embedded. Incubation for 36 h at 4°C. Requires antigen retrieval for paraformaldehyde-fixed specimens. Image courtesy of Dr. Holger Nilsson, University of Gothenburg.
Product Details
BEST-301AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within the last 50 amino acids from the C-terminus of rat Bestrophin-3 protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
BEST3 belongs to the bestrophin family of anion channels, which includes BEST1, the gene mutant in vitelliform macular dystrophy (VMD), and 2 other BEST1-like genes, BEST2 and BEST4. Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bestrophin-3; vitelliform macular dystrophy 2-like 3; Vitelliform macular dystrophy 2-like protein 3
Gene Aliases: Best3; mBest4; Vmd2l3
UniProt ID: (Mouse) Q6H1V1
Entrez Gene ID: (Mouse) 382427, (Rat) 314847
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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