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Alomone Labs, LTD
Beta 2 Na+/K+ ATPase (extracellular) Polyclonal Antibody
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Beta 2 Na+/K+ ATPase (extracellular) Antibody (ANP-012-200UL) in IHC (F)
Expression of Na+/K+ATPase beta 2 (ATP1B2) in mouse hippocampus - Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Anti-Beta 2 Na+/K+ATPase (extracellular) Antibody (#ANP-012), (1:300), followed by goat Anti-rabbit-AlexaFluor-488. ATP1B2staining (green) in the hippocampal CA1 region, is detected in glial cell profiles (horizontal arrows) in the stratum radiatum (SR) and pyram... View More
Product Details
ANP-012-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)DTESWDQHVQKLNK, corresponding to amino acid residues 99-112 of rat ATP1B2, Extracellular, C-terminus
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ ions across the plasma membrane. The exact function of the beta-2 subunit is not known. Mediates cell adhesion of neurons and astrocytes, and promotes neurite outgrowth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adhesion molecule in glia; adhesion molecule on glia; AMOG; ATPase, Na+/K+ transporting, beta 2 polypeptide; ATPase, Na+K+ transporting, beta polypeptide 2; glial cell adhesion molecule; Na, K-ATPase beta-2 polypeptide; snoRNA MBI-85; Sodium Potassium ATPase; sodium pump subunit beta-2; sodium-potassium ATPase subunit beta 2 (non-catalytic); sodium/potassium-dependent ATPase beta-2 subunit; Sodium/potassium-dependent ATPase subunit beta-2; sodium/potassium-transporting ATPase beta-2 chain; Sodium/potassium-transporting ATPase subunit beta-2
Gene Aliases: AMOG; ATP1B2; Atpb-2; ATPB2; ATPB2S; RATATPB2S
UniProt ID: (Human) P14415, (Mouse) P14231
Entrez Gene ID: (Human) 482, (Rat) 24214, (Mouse) 11932
potassium ion transport
cellular sodium ion homeostasis
cell adhesion
potassium ion import
cellular potassium ion homeostasis
positive regulation of ATPase activity
sodium ion transmembrane transport
sodium ion export from cell
protein stabilization
membrane repolarization
positive regulation of potassium ion transmembrane transporter activity
positive regulation of sodium ion export from cell
positive regulation of potassium ion import
transport
establishment or maintenance of transmembrane electrochemical gradient
ion transmembrane transport
leukocyte migration
cell communication by electrical coupling involved in cardiac conduction
ATP hydrolysis coupled transmembrane transport
regulation of cardiac conduction
ion transport
sodium ion transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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