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Invitrogen
Beta III Tubulin Polyclonal Antibody
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FIGURE: 1 / 2
Beta III Tubulin Antibody (PA5-143785) in ICC/IF
Immunocytochemistry analysis of Beta III Tubulin in aldehyde fixed and NP-40 permeabilized human NCI-H1299 lung carcinoma cells. The cells were labeled with rabbit polyclonal Beta III Tubulin polyclonal antibody (Product # PA5-143785). The antibody was detected using goat anti-rabbit DyLight® 594.
Product Details
PA5-143785
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Unphosphorylated betaIII-Tubulin synthetic peptide (coupled to KLH) corresponding to amino acid residues around serine 444 of human betaIII-Tubulin. This sequence is not found in bI or betaII-Tubulin isotypes, but is well conserved in betaIII-Tubulins from rat and mouse.
Conjugate
Form
Liquid
Concentration
~0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 1mg/mL BSA, 50% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2943013
Product Specific Information
This antibody was cross-adsorbed to phospho-betaIII-Tubulin (Ser-444) peptide before affinity purification using unphosphorylated betaIII-Tubulin (Ser-444) peptide (without carrier). The antibody detects a 50 kDa* protein corresponding to the molecular mass of unphosphorylated betaIII-Tubulin on SDS-PAGE immunoblots of purified brain tubulin and mouse brain tissue.
Target Information
The betaIII-tubulin isoform is present dominantly in cells of neuronal origin and it is one of the earliest markers of neuronal differentiation. It is regarded as a specific probe for the cells of neuronal origin as well as for the tumours originating from these cells. The betaIII-tubulin is most abundant in cells of neuronal origin, but was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: beta 3 tubulin; beta tubulin 3; betaIII-tubulin; class III beta-tubulin; MC1R; Neuron specific beta III Tubulin; Neuron-specific class III beta-tubulin; TUBB; tubulin beta; Tubulin beta-3; Tubulin beta-3 chain; Tubulin beta-4; Tubulin beta-4 chain; Tubulin beta-III; tubulin, beta 3 class III
Gene Aliases: 3200002H15Rik; beta-4; CDCBM; CDCBM1; CFEOM3; CFEOM3A; FEOM3; M(beta)3; M(beta)6; TUBB3; TUBB4
UniProt ID: (Human) Q13509, (Mouse) Q9ERD7, (Rat) Q4QRB4
Entrez Gene ID: (Human) 10381, (Mouse) 22152, (Rat) 246118
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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