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Product Details
BS-5993R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human HBEX2/Bex1, amino acids 55-125.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: brain expressed gene 1; brain expressed, X-linked 1; Brain-expressed X-linked protein 1; Brain-expressed X-linked protein 1 homolog; EG2RVC; H HGR74-h; ovarian granulosa cell 13.0 kDa protein hGR74; Protein BEX1; reduced expression 3; Reduced expression protein 3; REX-3
Gene Aliases: AA407839; AU018692; BEX1; BEX2; Bex4; HBEX2; HGR74-h; Rex3
UniProt ID: (Human) Q9HBH7, (Mouse) Q9R224, (Rat) Q3MKQ2
Entrez Gene ID: (Human) 55859, (Mouse) 19716, (Rat) 501625
positive regulation of neuroblast proliferation
multicellular organism development
nervous system development
cell differentiation
negative regulation of neuron differentiation
neurotrophin TRK receptor signaling pathway
positive regulation of transcription from RNA polymerase II promoter
positive regulation of sequence-specific DNA binding transcription factor activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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