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Product Details
651153
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
102.43
Immunogen
Butyrophilin Purified From Bovine Milk Fat Globule Membrane
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Recognizes butyrophilin, a unique 67 kD polypeptide present in lactating mammary gland epithelium and in the milk fat globule membrane (MFGM). No cross-reaction with other MFGM proteins. The epitope has been localized on the N-terminal extracellular part of the protein, close to the transmembrane region. Butyrophilins have recently been described as a new family of immunoregulators, similar to the co-stimulatory and co-inhibitory family of B7 molecules. Polypeptide reacting: Butyrophilin, 67 kD polypeptide; present in the apical membrane of lactating mammary epithelium and in MFGM.Reactivity on cultured cell lines: Transfected cell line BMGE with butyrophilin cDNA.Positive control: Milk fat globule membrane (MFGM).
Target Information
BTN1A1 (Butyrophilin) is the major protein associated with fat droplets in the milk. It is a member of the immunoglobulin superfamily. It may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bK14H9.2 (butyrophilin, subfamily 1, member A1); BT; Butyrophilin subfamily 1 member A1; butyrophilin, subfamily 1, member A1
Gene Aliases: BOS_21855; BT; BTN; BTN1; BTN1A1
UniProt ID: (Human) Q13410, (Bovine) P18892
Entrez Gene ID: (Human) 696, (Bovine) 282157
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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